Anabolic resistance does not explain sarcopenia in patients with type 2 diabetes mellitus, compared with healthy controls, despite reduced mTOR pathway activity [PDF]
BackgroundAgeing and type 2 diabetes mellitus (T2DM) are risk factors for skeletal muscle loss. We investigated whether anabolic resistance to feeding might underlie accelerated muscle loss in older people with T2DM and whether dysregulated mTOR ...
Babraj, John +3 more
core +4 more sources
Comprehensive Evidence for Mortality and Underlying Morbidity Related to Visceral Fat Distribution
ABSTRACT Linking obesity to mortality is an intriguing and controversial topic. This study tried to comprehensively assess 8 adiposity surrogates and mortality association among middle‐to‐old‐aged adults to identify a superior one, and explore explanatory disorders. Data sources included the National Health and Nutrition Examination Survey (NHANES), UK
Haolong Zhou +11 more
wiley +1 more source
Non-neural phenotype of spinal and bulbar muscular atrophy: Results from a large cohort of Italian patients [PDF]
Objective: To carry out a deep characterisation of the main androgen-responsive tissues involved in spinal and bulbar muscular atrophy (SBMA). Methods: 73 consecutive Italian patients underwent a full clinical protocol including biochemical and hormonal ...
Angelini, Lorenzo +37 more
core +1 more source
Bicomponent Mapping of Cortical Bone Using a New Interleaved UTE Imaging Sequence
ABSTRACT Purpose Ultrashort echo time (UTE) MRI enables direct imaging of cortical bone and quantification of its water compartments via bicomponent T2* modeling. However, conventional approaches require multiple separate dual‐echo scans due to limitations in gradient power. This approach is prone to inter‐scan inconsistencies such as motion and signal
Soo Hyun Shin +7 more
wiley +1 more source
Tomographic Measurements of Granular Flows in Gases and in Liquids
Two distinct non-intrusive radiation methods known as scanning gamma ray tomography and single profile photon absorptiometry are presented in this paper as tools for the investigation of interstitial voidage ...
Michail S. Nikitidis +3 more
doaj +1 more source
Objective Use of quantitative computed tomography (CT) to evaluate bone mineral density was suggested in the 1970s. Despite its reliability and accuracy, technical shortcomings restricted its usage, and dual-energy X-ray absorptiometry (DXA) became the ...
Sungjoon Lee +3 more
semanticscholar +1 more source
Mechanical suppression of osteolytic bone metastases in advanced breast cancer patients: A randomised controlled study protocol evaluating safety, feasibility and preliminary efficacy of exercise as a targeted medicine [PDF]
Background: Skeletal metastases present a major challenge for clinicians, representing an advanced and typically incurable stage of cancer. Bone is also the most common location for metastatic breast carcinoma, with skeletal lesions identified in over 80%
Chee, Raphael +11 more
core +7 more sources
Abstract Background Persons living with amyotrophic lateral sclerosis (PALS) are at high risk for malnutrition because of disease‐related factors such as dysphagia, self‐feeding difficulty, and hypermetabolism. Nutrition interventions, including enteral nutrition (EN) initiation after gastrostomy tube (G‐tube) placement, are integral to care but can ...
Stephanie Dobak +3 more
wiley +1 more source
To evaluate performance of anthropometric measures relative to percentage body fat (%BF) measured by dual‐energy X‐ray absorptiometry in children.
N. T. Tuấn, Youfa Wang
semanticscholar +1 more source
Abstract Background In individuals with cystic fibrosis (CF), lean mass and muscle strength are important predictors of clinical outcomes. This study evaluated associations among body composition, handgrip strength, muscle quality, physical activity, and health‐related quality of life in CF. Methods This observational, cross‐sectional study included 27
Benjamin H. Crain +9 more
wiley +1 more source

