Results 151 to 160 of about 94,612 (306)

Renal and Functional Vulnerability in Hansen Disease: A Framework for Chronic Infectious Disability in Endemic Settings

open access: yesTropical Medicine &International Health, EarlyView.
ABSTRACT Objectives Hansen disease is a neglected infectious disease associated with reactional inflammation, neuropathy and long‐term disability. Renal involvement and sarcopenia have been described separately, but their clinical coexistence has received limited attention. This review examines evidence for a hypothesised renal–functional vulnerability
Kleberson de Oliveira   +6 more
wiley   +1 more source

Body Composition Phenotypes and Their Metabolic Associations in Treatment-Naïve Patients With Newly Diagnosed Type 2 Diabetes: A DXA-Based Cluster Analysis. [PDF]

open access: yesEndocrinol Diabetes Metab
Using dual‐energy X‐ray absorptiometry clustering of 185 treatment‐naïve type 2 diabetes patients, we identified four body‐composition phenotypes. Central‐obesity and high‐fat–high‐muscle clusters carried the highest fatty liver disease and hyperuricemia risk, whereas the low‐muscle cluster carried the highest osteoporosis risk.
Zhang X, Zhang R, Jiang T.
europepmc   +2 more sources

Molecular pathophysiology of chronic kidney disease–mineral and bone disorder: Focus on the fibroblast growth factor 23–Klotho axis and bone turnover dynamics

open access: yesExperimental Physiology, EarlyView.
Abstract Chronic kidney disease–mineral and bone disorder (CKD‐MBD) is a major complication of chronic kidney disease (CKD), characterized by disruptions in mineral metabolism, abnormal bone turnover and vascular calcification, which collectively increase the risk of fractures and cardiovascular disease.
Alief Waitupu   +4 more
wiley   +1 more source

Whole body-dual energy X-ray absorptiometry to test body composition and bone mineral density in children with mucopolysaccharidosis type IV

open access: yes, 2001
The paper deals with whole body-dual energy X-ray absorptiometry applied in children with mucopolysaccharidosis type IV (or Morquio syndrome)
Rigante, D
core  

Seven days of mixed‐method heat acclimation improved markers of cardiovascular and fluid‐regulatory strain during exercise‐heat stress

open access: yesExperimental Physiology, EarlyView.
Abstract A mixed‐method heat acclimation (HA) protocol may optimise performance by supporting the training taper while promoting thermal adaptation; however, the impact on cardiovascular and fluid‐regulatory adjustments to protect health is unknown. Therefore, we examined the effects of a mixed‐method heat protocol on physiological responses, including
Daniel Snape   +5 more
wiley   +1 more source

A multi‐omics investigation of sarcopenia and frailty: Integrating genomic, epigenomic and telomere length data

open access: yesExperimental Physiology, EarlyView.
Abstract Sarcopenia and frailty are complex geriatric syndromes influenced by a combination of genetic and environmental factors. Recent studies suggest that specific genetic variants, DNA methylation patterns and shortened telomeres are associated with age‐related diseases and might contribute to the development of both sarcopenia and frailty. In this
Valentina Ginevičienė   +10 more
wiley   +1 more source

The effects of bed rest on cardiometabolic health: A systematic review and meta‐analysis

open access: yesExperimental Physiology, EarlyView.
Abstract Horizontal bed rest (HBR) and head‐down tilt (HDT) are models of physical inactivity. In this systematic review and meta‐analysis, we aimed to quantify changes in cardiometabolic outcomes during HBR and HDT in healthy adults. Following the PRISMA guidelines, we searched PubMed, Scopus, Web of Science and Cochrane Library until 1 October 2025 ...
Konstantinos Prokopidis   +7 more
wiley   +1 more source

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