Effects of Nandrolone Decanoate on Muscle Strength, Body Composition and Bone Density: A Systematic Review and Meta-Analysis. [PDF]
ABSTRACT Background Despite ongoing interest in anabolic therapies for sarcopenia and cachexia, pharmacological interventions are being developed to counteract age‐ and condition‐related losses of muscle mass and strength. This systematic review and meta‐analysis evaluated the effect of nandrolone decanoate on lean soft tissue (LST), fat mass, handgrip
Prokopidis K +13 more
europepmc +2 more sources
Reference Methods for Measuring Skeletal Muscle Mass: A Critical Perspective. [PDF]
ABSTRACT Skeletal muscle (SM) is an integral organ component in the pathophysiology of many acute and chronic diseases. But is there a ‘gold’ standard or accepted reference method for quantifying the amount and composition of human SM mass? Exploring that question led us to recognize the existence of a SM measurement paradigm that divides methods into ...
Heymsfield SB +7 more
europepmc +2 more sources
Evaluation of Skinfolds Based Predictive Equations for Estimating Body Fat Percentage in Older Adults: A Comparison Using Digital Adipometer (Lipowise) and Dual-Energy X-Ray Absorptiometry (DXA). [PDF]
ABSTRACT Accurate assessment of body fat percentage (%BF) is essential for predicting health risks in older adults, as age‐related changes affect fat distribution and measurement accuracy. While dual‐energy x‐ray absorptiometry (DXA) is a standard reference, it is costly and less accessible.
de Oliveira GB +4 more
europepmc +2 more sources
Primary Hyperparathyroidism in Adults: Recent Developments in Diagnosis and Management. [PDF]
ABSTRACT Primary hyperparathyroidism has a prevalence of around 1% in the general population. Diagnosis requires biochemical testing of serum (for calcium and parathyroid hormone) and urine (for calcium excretion), as well as wider screening for complications including osteoporosis, renal disease, abdominal symptoms and neuropsychiatric disturbance. In
Wootton E +5 more
europepmc +2 more sources
ABSTRACT Artificial intelligence (AI) enables automated, high‐throughput adiposity quantification, offering refined risk stratification for women with overweight and obesity. We systematically reviewed and meta‐analyzed studies evaluating AI‐based segmentation of visceral, subcutaneous, and total fat in adult women populations (BMI: 25–29.9 and ≥ 30 kg/
Asefa Adimasu Taddese, Bjorn T. Tam
wiley +1 more source
ABSTRACT Aims This study examined changes in body composition and bone mineral density (BMD) over 12 months in people with obesity and type 1 diabetes (T1D) treated with a GLP‐1 receptor agonist alone (GLP‐1RA) or a dual glucose‐dependent insulinotropic polypeptide (GIP/GLP‐1RA).
Ebaa Al Ozairi +5 more
wiley +1 more source
Advanced Molecular Imaging Probes for Skeletal Diseases: Current Progress and Future Perspectives
This review summarizes the potential molecular imaging techniques and probes for common orthopedic diseases, such as trauma, infection, metabolism, tumor, joint, spine and other fields, aiming to provide a basis for the development of a new generation of molecular imaging probes.
Shuo Guo +6 more
wiley +1 more source
Bone Organoids: A Novel Tool for Modeling and Managing Skeletal Disorders in Diabetes
This review synthesizes advances in bone organoid engineering and evaluates their potential to model diabetic bone fragility. Current in vitro and animal models do not fully recapitulate diabetes‐associated skeletal phenotypes. Cell‐based and scaffold‐based bone organoids are discussed as complementary approaches to reconstruct multicellular bone ...
Shuangzhe Lin +2 more
wiley +1 more source
ABSTRACT Background Management of sarcopenia by nutritional and lifestyle interventions is a challenge. The aim is to assess the effectiveness of a phenolic‐rich extra virgin olive oil (EVOO), alone or combined with a prebiotic (PREB) (fructooligosaccharides and inulin), to improve skeletal muscle mass and function in home‐dwelling older adults (60–80 ...
Maria Besora‐Moreno +12 more
wiley +1 more source
BMD in Transient Osteoporosis and Bone Marrow Edema Syndrome: A Scoping Review
Transient osteoporosis of the hip (TOH), regional migratory osteoporosis (RMO), and bone marrow edema syndrome (BMES) are increasingly recognized as manifestations of the same underlying condition. Hallmark features include joint pain, bone marrow edema on MRI, and localized demineralization.
Eivind Hasvik +3 more
wiley +1 more source

