Results 191 to 200 of about 1,827,815 (335)

Cluster‐Mediated Solute Stabilization and Shear‐Bypass Synergistic Strengthening in High‐Alloyed Systems

open access: yesAdvanced Science, EarlyView.
This study demonstrates that in high‐alloy systems, nanoclusters with high solute tolerance can effectively suppress compositional segregation. This mitigation leads to a concurrent 18.7% increase in strength and 41.5% improvement in ductility, which is attributed to a shear‐bypass synergistic strengthening mechanism. The findings provide a new pathway
Wei Yu   +10 more
wiley   +1 more source

Nanomedicine Meets Immunotherapy: Advancing Adoptive Cell Therapy with Nanoparticles in the Treatment of Cancer with Sustainability Perspectives

open access: yesAdvanced Science, EarlyView.
This review surveys nanoparticle‐based strategies to enhance adoptive cell therapy, particularly CAR‐T cell approaches, in solid tumor treatment. It describes how nanoparticles can improve tumor immunogenicity and T‐cell infiltration while reducing toxicity, and how they enable in vivo CAR‐T cell generation.
Erica Frostegård   +19 more
wiley   +1 more source

NIR‐II Imaging‐Guided Photothermal Activation of a TRPV4‐Targeted Nanoplatform Delivering Cycloastragenol to Promote Microglia Reprogramming and α‐Synuclein Clearance in Parkinson's Disease

open access: yesAdvanced Science, EarlyView.
ABSTRACT Current therapies for Parkinson's disease (PD) fail to concurrently address α‐synuclein (α‐syn) aggregation and microglia‐mediated neuroinflammation. Herein, we engineer a near‐infrared‐II (NIR‐II) phototheranostic nanoplatform, CAG/FD1080@MM‐aTRPV4, for synergistic regulation of microglial function and real‐time monitoring of PD pathology. We
Hsuan Lo   +9 more
wiley   +1 more source

Soft Robotics and Advanced Technologies for Minimally Invasive Bioprinting: The Future of Internal Organ Repair

open access: yesAdvanced Science, EarlyView.
This review examines the evolution of bioprinting toward minimally invasive in situ strategies for internal organ regeneration. It defines the technological roadmap from handheld systems to advanced minimally invasive bioprinting platforms, positioning soft robotics as a core enabler.
Duc Tu Vu   +9 more
wiley   +1 more source

Targeted Thrombolysis via CCR2‐Engineered Macrophage‐Mimicking Microbubbles Safely Ablates Venous, Arterial, and Microvascular Thrombosis

open access: yesAdvanced Science, EarlyView.
CCR2‐Enhanced Macrophage Membrane–Camouflaged Microbubbles for MCP‐1–Mediated Thrombus Targeting and Ultrasound‐Triggered Urokinase Release. ABSTRACT The clinical management of thrombosis, a primary cause of death worldwide, is hampered by the limitations of current thrombolytic agents, including short half‐life and high risk of off‐target bleeding ...
Buying Li   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy