Results 71 to 80 of about 3,260,990 (309)

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

KilonovAE: Exploring Kilonova Spectral Features with Autoencoders

The Astrophysical Journal
Kilonovae are likely a key site of heavy r -process element production in the Universe, and their optical/infrared spectra contain insights into both the properties of the ejecta and the conditions of the r -process. However, the event GW170817/AT2017gfo
N. M. Ford, Nicholas Vieira, John J. Ruan, Daryl Haggard   +3 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

INVESTIGATION OF DIFFUSE INTERSTELLAR BANDS OF ORGANIC MOLECULES IN THE SPECTRA OF CEPHEID STARS

Odessa Astronomical Publications, 2016
We describe an effective method of investigation of the Diffuse Interstellar Bands (DIBs) in the spectra of Cepheid stars. DIBs are believed to originate from the absorption of such carriers as polycyclic aromatic hydrocarbons in the interstellar gaseous
S. V. Kashuba, S. M. Andrievsky, F. A. Chekhonadskikh, S. A. Korotin, V. V. Kovtyukh, R. E. Luck   +5 more
doaj   +1 more source

Interpretation of europium(III) spectra

, 2015
The trivalent europium ion (Eu 3+ ) is well known for its strong luminescence in the red spectral region, but this ion is also interesting from a theoretical point of view.
K. Binnemans
semanticscholar   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Optical Absorption of the Antitrypanocidal Drug Benznidazole inWater

Molecules, 2014
UV-vis optical absorption spectra of the antitrypanocidal drug benznidazole solvated in water were measured for various concentrations. The spectra show a prominent peak around 3.80 eV, while deconvolution of the UV-vis optical absorption spectra ...
Eveline M. Bezerra, João R. Bezerra-Neto, Francisco A. M. Sales, Ricardo P. dos Santos, Alice M. C. Martins, Pedro de Lima-Neto, Ewerton W. S. Caetano, Eudenilson L. Albuquerque, Valder N. Freire   +8 more
doaj   +1 more source

Infrared Absorption Spectra of Monohydric Alcohols

, 2013
FTIR spectra of homologous series of monohydric alcohols which belong to the class of partly ordered liquids were registered. The molecules of monohydric alcohols containing hydroxyl group are able to form hydrogen-bonded clusters in the condensed phase.
I. Doroshenko, V. Pogorelov, V. Šablinskas   +2 more
semanticscholar   +1 more source