Results 41 to 50 of about 109,366 (301)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Structural analysis of the impact of learning from errors and organizational failures on innovative performance with the mediation role of knowledge absorptive capacity (case study: cooperative companies) [PDF]

open access: yesمدیریت نوآوری و راهبردهای عملیاتی
Purpose: Learning from failures and errors is a sustainable source of knowledge for organizations, leading to an increase in employees' absorptive capacity.
Sara Mohammadi   +3 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

The impacts of the antecedents on absorptive capacity and export performance: a meta-analytic review

open access: yesSHS Web of Conferences, 2017
Although exporting performance and absorptive capacity, with its relevant antecedents have been studied extensively, rare of them have integrated these variables into a more comprehensive framework. Not only this study aims to synthesize extant knowledge
Wann-Yih Wu, Yani Permatasari
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Bibliometric analysis of absorptive capacity

open access: yesInternational Business Review, 2017
Abstract This study contributes to our understanding of absorptive capacity (AC) by reviewing AC articles systematically using two types of blibliometric co-citation analysis – bibliometric co-citation and bibliometric cartography – for the last 25 years.
Apriliyanti, Indri, Alon, Ilan
openaire   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Big Push versus Absorptive Capacity: How to Reconcile the Two Approaches [PDF]

open access: yes
In this paper we examine whether absorptive capacity can constitute sufficient justification for rejecting the proposal of a large aid increase to support the ?big push?.
Guillaumont Jeanneney, Sylviane   +1 more
core   +6 more sources

HUBUNGAN ANTARA KNOWLEDGE SHARING CAPABILITY, ABSORPTIVE CAPACITY DAN MEKANISME FORMAL: STUDI KASUS INDUSTRI TEKNOLOGI INFORMASI DAN KOMUNIKASI DI INDONESIA

open access: yesJurnal Teknik Industri, 2008
Knowledge is currently viewed as an important strategic resource in companies in order to gain competitive advantage. However, the success in generating competitive advantage will depend on the company’s ability to acquire and assimilate knowledge ...
Luciana Andrawina   +3 more
doaj  

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