Introduction Injection drug users (IDUs) often develop acute bacterial skin and skin structure infections (ABSSSI) and use emergency departments as their primary source for medical care.
Gregory J. Moran +5 more
doaj +1 more source
The efficacy and adverse events of delafloxacin for treating acute bacterial skin and skin structure infections : a systematic review and meta-analysis [PDF]
Background: Acute bacterial skin and skin structure infections (ABSSSI) cause significant morbidity and mortality in hospitalized patients and outpatients as well.
Cammarata +7 more
core +2 more sources
Efficacy and safety of dalbavancin in the treatment of acute bacterial skin and skin structure infections (ABSSSIs) and other infections in a real-life setting: data from an Italian observational multicentric study (DALBITA study) [PDF]
Objectives: We evaluated the efficacy and safety of dalbavancin in ABSSSI and ‘other sites’ infections’ (OTA). Methods: Observational study involving 11 Italian hospitals including patients that received ≥1 dose of dalbavancin in 2016–2019.
Aldieri C. +19 more
core +2 more sources
Ceftaroline Fosamil for Treatment of Pediatric Complicated Skin and Soft Tissue Infections and Community-Acquired Pneumonia [PDF]
Community-acquired pneumonia (CAP)/community-acquired bacterial pneumonia (CABP) and complicated skin and soft tissue infection (cSSTI)/acute bacterial skin and skin structure infection (ABSSSI) represent major causes of morbidity and mortality in ...
Carrothers T. J. +4 more
core +1 more source
β-Lactam Monotherapy vs β-Lactam-Macrolide Combination Treatment in Moderately Severe Community-Acquired Pneumonia: A Randomized Noninferiority Trial. [PDF]
IMPORTANCE: The clinical benefit of adding a macrolide to a β-lactam for empirical treatment of moderately severe community-acquired pneumonia remains controversial.
Carballo, S. +13 more
core +2 more sources
: Background: Surgical wound dehiscence (SWD) is one of the most common complications of surgical incision sites after foot surgeries because of blood flow and circulation issues that may occur in the foot. Such SWD complications can potentially lead to
Philip Wrotslavsky
doaj +1 more source
Use of lipoglycopeptides for moderate to severe ABSSSI in the emergency department
The burden of acute bacterial skin and skin structure infections (ABSSSI) continue to plague the healthcare system. One approach to managing moderate-to-severe ABSSSI in low-risk patients involves use of a single dose lipoglycopeptide (LGP), dalbavancin or oritavancin, in the emergency department (ED) and discharge to home with follow-up care.
Cierra N, Treu +3 more
openaire +2 more sources
Acute bacterial skin and skin structure infections: current perspective
A skin and skin structure infection is a bacterial infection of skin and associated tissues. It may be complicated skin and skin structure infection or uncomplicated skin and skin structure infection. Recently, the Food and Drug Administration has called
Megha Shah, Hetal D Shah
doaj +1 more source
Efficacy and safety of delafloxacin compared with vancomycin plus aztreonam for acute bacterial skin and skin structure infections : A Phase 3, double-blind, randomized study [PDF]
Funding Information: This work was funded by Melinta Therapeutics. In addition the editorial assistance (see below) was funded by Melinta Therapeutics.
Gardovskis, J., PROCEED Study Group
core +1 more source
Innovative Wirkstoffe aus der antibakteriellen Forschung im Kampf gegen mikrobielle Resistenzen
Dieser Artikel gewährt einen Überblick über in den letzten drei Jahrzehnten untersuchte antibakteriellen Wirkstoffe. Aspekte der Herkunft, der zellulären Targetstrukturen, des antibakteriellen Wirkspektrums und dem Nachweis der Wirksamkeit in Tierstudien werden zusammen mit aktuellen Entwicklungen beleuchtet.
Roderich D. Süssmuth +3 more
wiley +1 more source

