Results 41 to 50 of about 1,169,039 (310)

Parent‐to‐Child Information Disclosure in Pediatric Oncology

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Despite professional consensus regarding the importance of open communication with pediatric cancer patients about their disease, actual practice patterns of disclosure are understudied. Extant literature suggests a significant proportion of children are not told about their diagnosis/prognosis, which is purported to negatively ...
Rachel A. Kentor, Flora Hoodin, Michelle Byrd, Kristin A. Kullgren, Leah LaLonde, Lauren Benkoske, Patrick Smith, Dawn Carson, Karen MacDonald, Susumu Inoue, Brenda Kitchen, Kate Gowans, Gregory A. Yanik   +12 more
wiley   +1 more source

scPriorGraph: constructing biosemantic cell–cell graphs with prior gene set selection for cell type identification from scRNA-seq data

Genome Biology
Cell type identification is an indispensable analytical step in single-cell data analyses. To address the high noise stemming from gene expression data, existing computational methods often overlook the biologically meaningful relationships between genes,
Xiyue Cao, Yu-An Huang, Zhu-Hong You, Xuequn Shang, Lun Hu, Peng-Wei Hu, Zhi-An Huang   +6 more
doaj   +1 more source

Cell type-specific epigenetic links to schizophrenia risk in the brain

Genome Biology, 2019
Background The importance of cell type-specific epigenetic variation of non-coding regions in neuropsychiatric disorders is increasingly appreciated, yet data from disease brains are conspicuously lacking.
Isabel Mendizabal, Stefano Berto, Noriyoshi Usui, Kazuya Toriumi, Paramita Chatterjee, Connor Douglas, Iksoo Huh, Hyeonsoo Jeong, Thomas Layman, Carol A. Tamminga, Todd M. Preuss, Genevieve Konopka, Soojin V. Yi   +12 more
doaj   +1 more source

Are we survivors of the sudden past singularity?

European Physical Journal C: Particles and Fields, 2023
In this paper, we investigate the viability of cosmological models featuring a type II singularity that occurs during the past evolution of the Universe.
Adam Balcerzak, Tomasz Denkiewicz, Mateusz Lisaj   +2 more
doaj   +1 more source

A Systematic Review of Evidence on the Clinical Effectiveness of Surveillance Imaging in Children With Medulloblastoma and Ependymoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Surveillance imaging aims to detect tumour relapse before symptoms develop, but it's unclear whether earlier detection of relapse leads to better outcomes in children and young people (CYP) with medulloblastoma and ependymoma. This systematic review aims to identify relevant literature to determine the efficacy of surveillance magnetic ...
Lucy Shepherd, Melissa Taylor, Helen Fulbright, Bob Phillips   +3 more
wiley   +1 more source

Cell type-specific inference from bulk RNA-sequencing data by integrating single-cell reference profiles via EPIC-unmix

Genome Biology
Cell type-specific analysis is crucial for uncovering biological insights hidden in bulk tissue data, yet single-cell or single-nuclei approaches are often cost-prohibitive for large samples.
Chenwei Tang, Quan Sun, Xinyue Zeng, Gang Li, Xiaoyu Yang, Fei Liu, Jinying Zhao, Yin Shen, Boxiang Liu, Jia Wen, Yun Li   +10 more
doaj   +1 more source

Jenis Proposisi Dalam Karangan Argumentasi Siswa

Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan, 2019
: This research was aimed to describe the type of proposition on argumentative text of students. This study is a text analysis study. The data of the study was the sentence of students’ argumentative text.
Syahruddin Syahruddin, Sumadi Sumadi, Sunaryo Sunaryo   +2 more
doaj   +1 more source

DeCAF: a novel method to identify cell-type specific regulatory variants and their role in cancer risk

Genome Biology, 2022
Here, we propose DeCAF (DEconvoluted cell type Allele specific Function), a new method to identify cell-fraction (cf) QTLs in tumors by leveraging both allelic and total expression information.
Cynthia A. Kalita, Alexander Gusev
doaj   +1 more source

Prognostic Impact of Treatment Modalities, Including Targeted Compartmental Radio‐Immunotherapy, in a Cohort of Neuroblastoma Patients With CNS Metastases at Relapse

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Neuroblastoma (NB) with central nervous system (CNS) metastases is rare at diagnosis, but occurs more often during relapse/progression. Patients with CNS metastases face a dismal prognosis, with no standardized curative treatment available.
Vicente Santa‐Maria Lopez, Anna Felip‐Badia, Marina Caballero‐Bellon, Nazaret Sanchez‐Sierra, Alicia Castañeda, Moira Garraus, Maite Gorostegui, Margarida Simão‐Rafael, Juan Pablo Muñoz, Marta Perez‐Somarriba, Salvador Mañe, Mariana Cecilia Planells, Sara Perez‐Jaume, Jaume Mora   +13 more
wiley   +1 more source

Class-Diagrams for Abstract Data Types [PDF]

, 2017
We propose to extend iUML-B class-diagrams to elaborate Abstract Data Types (ADTs) specified using Event-B theories. Classes are linked to data types, while attributes and associations correspond to operators of the data types. Axioms about the data types and operators are specified as constraints on the class.
Hoang, Thai Son, Snook, Colin, Dghaym, Dana, Butler, Michael   +3 more
openaire   +2 more sources