Results 41 to 50 of about 5,183,162 (349)

Leveraging current insights on IL‐10‐producing dendritic cells for developing effective immunotherapeutic approaches

open access: yesFEBS Letters, EarlyView.
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali   +3 more
wiley   +1 more source

Tipo abstracto de datos "Biblioteca" Library Abstract data type

open access: yesInformación, Cultura y Sociedad, 2010
Análisis de la descripción bibliográfica desde un punto de vista conceptual a partir de la especificación formal: tipo abstracto de datos "biblioteca". Se detallan otros abordajes usando el modelo entidad-relación y el lenguaje XML.
Silvana Temesio Vizoso
doaj  

FoxO1 signaling in B cell malignancies and its therapeutic targeting

open access: yesFEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac   +3 more
wiley   +1 more source

A Comparison of Different Station Data on Revealing the Characteristics of Extreme Hourly Precipitation Over Complex Terrain: The Case of Zhejiang, China

open access: yesEarth and Space Science, 2023
Both long‐term but small number of national stations and short‐term but large number of regional stations have been frequently used to study the extreme hourly precipitation (EXHP) in China.
Mengwen Wu   +4 more
doaj   +1 more source

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

Verification of Backtracking and Branch and Bound Design Templates

open access: yesМоделирование и анализ информационных систем, 2011
The Design and Analysis of Computer Algorithms is a must of Computer Curricula. It covers many topics that group around several core themes. These themes range from data structures to the complexity theory, but one very special theme is algorithmic ...
N. V. Shilov
doaj  

TORC: Target-Oriented Reference Construction for supervised cell-type identification in scRNA-seq

open access: yesGenome Biology
Cell-type identification is a crucial step in single cell RNA-seq (scRNA-seq) data analysis, for which supervised methods are preferred due to their accuracy and efficiency.
Xin Wei, Wenjing Ma, Zhijin Wu, Hao Wu
doaj   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

The thioredoxin‐like and one glutaredoxin domain are required to rescue the iron‐starvation phenotype of HeLa GLRX3 knock out cells

open access: yesFEBS Letters, EarlyView.
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt   +4 more
wiley   +1 more source

Disease associations depend on visit type: results from a visit-wide association study

open access: yesBioData Mining, 2019
Introduction Widespread adoption of Electronic Health Records (EHR) increased the number of reported disease association studies, or Phenome-Wide Association Studies (PheWAS).
Mary Regina Boland   +4 more
doaj   +1 more source

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