Results 101 to 110 of about 8,638,029 (373)

Machine learning of neuroimaging for assisted diagnosis of cognitive impairment and dementia: A systematic review

Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, 2018
Introduction Advanced machine learning methods might help to identify dementia risk from neuroimaging, but their accuracy to date is unclear.
Enrico Pellegrini, Lucia Ballerini, Maria del C. Valdes Hernandez, Francesca M. Chappell, Victor González‐Castro, Devasuda Anblagan, Samuel Danso, Susana Muñoz‐Maniega, Dominic Job, Cyril Pernet, Grant Mair, Tom J. MacGillivray, Emanuele Trucco, Joanna M. Wardlaw   +13 more
doaj   +1 more source

A Fully Abstract Symbolic Semantics for Psi-Calculi

, 2010
We present a symbolic transition system and bisimulation equivalence for psi-calculi, and show that it is fully abstract with respect to bisimulation congruence in the non-symbolic semantics.
A. M. Pitts, Bartek Klin, Björn Victor, Björn Victor, Bruno Blanchet, Bruno Blanchet, Davide Sangiorgi, Huimin Lin, Huimin Lin, Jesper Bengtson, Jesper Bengtson, Joachim Parrow, Johannes Borgström, Johannes Borgström, Johannes Borgström, Magnus Johansson, Maria Grazia Buscemi, Mart'ı n Abadi, Mart'ı n Abadi, Mart'ı n Abadi, Mathieu Baudet, Matthew Hennessy, Michele Boreale, Murdoch Gabbay, Paweł Sobociński, Stéphanie Delaune, Sébastien Briais   +26 more
core   +3 more sources

Comprehensive profiling of lncRNAs and mRNAs enriched in small extracellular vesicles for early noninvasive detection of colorectal cancer: diagnostic panel assembly and extensive validation

Molecular Oncology, EarlyView.
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova, Marketa Pavlikova, Lucie Pifkova, Robin Jugas, Tana Machackova, Lenka Radova, Milana Sachlova, Renata Bartosova, Tetiana Samoilenko, Zuzana Feckova, Jana Orlickova, Erika Slamova, Elleni Ponechal Michu, Dagmar Al Tukmachi, Michaela Ruckova, Martina Vodinska, Jan Kotoucek, Tina Catela Ivkovic, Marie Boudna, Lucia Bohovicova, Teodor Stanek, Jana Halamkova, Martin Svoboda, Vladimir Prochazka, Tomas Grolich, Zdenek Kala, Ondrej Slaby   +26 more
wiley   +1 more source

The critical role of DNA damage‐inducible transcript 4 (DDIT4) in stemness character of leukemia cells and leukemia initiation

Molecular Oncology, EarlyView.
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li, Zhijie Cao, Haiyan Xing, Zhenya Xue, Wenbing Liu, Jiayuan Chen, Yihan Mei, Runxia Gu, Hui Wei, Shaowei Qiu, Min Wang, Qing Rao, Jianxiang Wang   +12 more
wiley   +1 more source

ANN for Predicting Antibiotic Susceptibility [PDF]

, 2016
: In this research, an Artificial Neural Network (ANN) model was developed and tested to predict efficiency of antibiotics in treating various bacteria types. Attributes that were taken in account are: organism name, specimen type, and antibiotic name as
Ahmed, Maaruf, Randa, Qassas
core  

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

Molecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi, Mirjam Balbisi, Simon Sugár, Lóránd Váncza, Eszter Regős, Ilona Kovalszky, Ibolya Laczó, Tünde Harkó, Gábor Kecskeméti, Zoltán Szabó, Judit Moldvay, László Drahos, Lilla Turiák   +12 more
wiley   +1 more source

Asynchronous data retrieval from an object-oriented database [PDF]

, 1988
We present an object-oriented semantic database model which, similar to other object-oriented systems, combines the virtues of four concepts: the functional data model, a property inheritance hierarchy, abstract data types and message-driven computation.
Bic, Lubomir, Gilbert, Jonathan P.
core  

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source

The prominent pervasive oncogenic role and tissue specific permissiveness of RAS gene mutations

Scientific Reports
In cancer research, RAS biology has been focused on only a handful of tumor types. While RAS genes have long been suspected as common contributors to a wide spectrum of cancer types, robust evidence is required to firmly establish their critical ...
Ming Yi, Daniel Soppet, Frank McCormick, Dwight V. Nissley   +3 more
doaj   +1 more source

Algebraic implementation of abstract data types [PDF]

, 1979
Hartmut Ehrig, Hans‐Jörg Kreowski, Peter Padawitz   +2 more
openalex   +1 more source