Results 141 to 150 of about 761,584 (320)
Long‐Term Evaluation of Givinostat in Duchenne Muscular Dystrophy, and Natural History Comparisons
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives This ongoing, open‐label extension study is evaluating the long‐term safety, tolerability, and efficacy of givinostat, a Class I and II histone deacetylase inhibitor, in patients with Duchenne muscular dystrophy (DMD). Methods The recruited patients completed one of two prior clinical studies (one Phase 2 and one Phase 3 [EPIDYS ...
Craig M. McDonald +74 more
wiley +1 more source
Catalyses by Polymer Complexes. VI. Catalysis of Proton Abstraction from α-Ketols by Hydroxamate Ions Bound to Polymer Micelles [PDF]
, 1977 Seiji Shinkai, Toyoki Kunitake
openalex +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Recurrent high‐grade gliomas have a poor prognosis and limited therapeutic options. This study aimed to evaluate the safety and efficacy of SYHA1813, a dual inhibitor of VEGFR and CSF1R, in patients with recurrent high‐grade gliomas.
Zhuang Kang +16 more
wiley +1 more source
Search for low activation energy abstraction of H from C–H bonds by D atoms in hydrocarbons at 77 K [PDF]
, 1976 D. D. Wilkey, J. E. Willard
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Temporal logic with predicate abstraction
, 2004 A predicate linear temporal logic LTL_{\lambda,=} without quantifiers but with predicate abstraction mechanism and equality is considered. The models of LTL_{\lambda,=} can be naturally seen as the systems of pebbles (flexible constants) moving over the ...
Lisitsa, Alexei, Potapov, Igor
core +2 more sources
Durability of Response to B‐Cell Maturation Antigen‐Directed mRNA Cell Therapy in Myasthenia Gravis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective We report the 12‐month follow‐up outcomes from a Phase 2 clinical trial (NCT04146051) evaluating Descartes‐08, a BCMA‐directed RNA chimeric antigen receptor T‐cell (rCAR‐T) therapy for refractory generalized myasthenia gravis (MG).
Nizar Chahin +10 more
wiley +1 more source
Hydrogen Atom Abstraction ofp-Chloranil Triplet in 1,4-Dioxane in the Presence and Absence of Tetrachlorohydroquinone [PDF]
, 1979 Harumichi Kobashi +2 more
openalex +1 more source
Probabilistic Program Abstractions
, 2017 ion is a fundamental tool for reasoning about complex systems. Program abstraction has been utilized to great effect for analyzing deterministic programs.
Broeck, Guy Van den +2 more
core
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Autosomal dominant progranulin (GRN) pathogenic variants are a genetic cause of frontotemporal lobar degeneration. Though clinical trials for GRN‐related therapies are underway, there is an unmet need for biomarkers that can predict symptom onset and track disease progression.
Taru M. Flagan +46 more
wiley +1 more source