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ABSTRACT In the phase 2, double‐blind, randomized controlled BEYOND trial (NCT03342404), luspatercept increased hemoglobin levels in patients with non‐transfusion‐dependent β‐thalassemia (NTDT). This study assessed long‐term effects of luspatercept on patient‐reported outcomes (PROs), using data from BEYOND and patients who continued luspatercept ...
Khaled M. Musallam +12 more
wiley +1 more source
International Labor Migration: A Responsible Role for Business [PDF]
Outlines trends in labor migration in international supply chains and proposes an action plan for businesses to raise awareness and engage with suppliers to protect foreign workers' rights.
Chris Nolan, Racheal Yeager
core
Arsenite methyltransferase 3 is required for mitochondrial function and hepatic lipid metabolism
AS3MT is a protein that helps the body process arsenic, a naturally occurring toxin found in water and soil. We discovered it also helps cells make and use energy properly. Without AS3MT, cells' mitochondria do not work well, leading to fatty liver and reduced activity. Increasing AS3MT in liver cells restores energy and protects against arsenic damage,
Patrice Delaney +10 more
wiley +1 more source
Transcontinentales : Pourriez-vous nous eclairer sur la genese du projet Louvre Abu Dhabi, son contenu et ses partenariats en France et aux Emirats ? Catherine Guillou : Le projet du Louvre Abu Dhabi emane d’un accord intergouvernemental entre la France et les Emirats arabes unis [accord signe le 6 mars 2007].
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Investing in a More Robust Public Policy Environment in the Middle East [PDF]
Outlines considerations for funders with respect to the development of human capital and strengthening civil society organizations, including the need for long-term, targeted, and sustained investment as well as funder ...
Jon B. Alterman
core
We investigated the potential of iloperidone as an activator of Sigma‐1 receptor (S1R) neuroprotective function in juvenile Huntington's disease (jHD). We tested iloperidone on cortical neurons differentiated from patient‐derived iPSCs, demonstrating that it acts as a S1R agonist, decreasing apoptosis, huntingtin aggregation, and oxidative stress ...
Ersilia Fornetti +11 more
wiley +1 more source
Manifest Destiny in American Higher Education: Elite Tertiary Institutions and the Branch Campus Phenomenon [PDF]
American colleges and universities are increasingly looking overseas to form collaborative partnerships that can enhance institutional prestige and increase revenue.
Alexis Brooke Redding
core
Revisiting Asset Pricing Models: The Case for an Intangibles Factor
ABSTRACT In an increasingly knowledge‐based economy, intangible assets may be an important driver of firm performance and stock returns. We introduce an intangibles intensity factor (INT), distinct from the organization capital factor, and show that exposure to this factor strongly predicts stock returns, outperforming traditional factors.
Dion Bongaerts +2 more
wiley +1 more source
Gesture-controlled omnidirectional autonomous vehicle: A web-based approach for gesture recognition
This paper presents a novel web-based hand/thumb gesture recognition model, validated through the implementation of a gesture-controlled omnidirectional autonomous vehicle.
Huma Zia +7 more
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