Results 121 to 130 of about 247,562 (228)

Positive modulation of glucagon‐like peptide 1 (GLP‐1) receptor by endogenous haemorphins with implications in glucose metabolism and diabetes

open access: yesBritish Journal of Pharmacology, EarlyView.
Haemorphins act on GLP‐1 receptor (GLP‐1R) activity and signalling in a positive allosteric manner. This leads to potentiated GLP‐1‐mediated activity and signalling, as well as insulin synthesis, which may have implications for glucose metabolism and, thereby, diabetes and obesity. (The graph was created in BioRender.com).
Farheen Badrealam Khan   +13 more
wiley   +1 more source

First eDNA-based monitoring of marine vertebrates in the urban marine ecosystem of Abu Dhabi: Mangrove and seagrass beds as biodiversity reservoirs? [PDF]

open access: yesPLoS One
Jung JL   +11 more
europepmc   +1 more source

Pest‐preservation paradox among insects

open access: yesConservation Biology, EarlyView.
The pest‐preservation paradox is a non‐binary perspective that insects range from those that are harmful and requiring management on the one side, to those requiring conservation intervention on the opposite end of the spectrum. Importantly, the vast majority of insects occur somewhere in the center of the two extremes, and their position along the ...
Michael J. Samways   +3 more
wiley   +1 more source

Design and usability of Abu Dhabi Food Intake24: a culturally adapted digital 24-hour dietary recall for the United Arab Emirates. [PDF]

open access: yesFront Nutr
Ali HI   +7 more
europepmc   +1 more source

In Defence of Oblique Intention

open access: yesEuropean Journal of Philosophy, EarlyView.
Abstract Recent work on lying has revived an old action‐theoretic category: oblique, or indirect, intention. I argue that some liars intend deception obliquely. Sneddon objects that this category is drastic and unjustified: it counts all foreseen side‐effects as intended. My response is that oblique intention is not mere foresight.
Vladimir Krstić
wiley   +1 more source

Optimizing Strategies for Managing Difficult Intravenous Access

open access: yesRisk Management and Healthcare Policy
Ahmed Alaaeldin Saad,1 Mecit Can Emre Simsekler,1 Sundos Ahmed,2 Rawaa Ouda,2 Omar Khaddam,2 Mohamed Sanousi,3 Mini Benny,4 Hani Abdalla Sunbati,4 Deanne Kashiwagi,5 Ahmad Al Rifai,2 Masood Ahmad,6 Siddiq Anwar2 1Department of Management Science ...
Saad AA   +11 more
doaj  

Determinants of mental health distress among health workers in Abu Dhabi, United Arab Emirates. [PDF]

open access: yesFront Psychiatry
Masuadi E   +4 more
europepmc   +1 more source

Arsenite methyltransferase 3 is required for mitochondrial function and hepatic lipid metabolism

open access: yesThe FEBS Journal, EarlyView.
AS3MT is a protein that helps the body process arsenic, a naturally occurring toxin found in water and soil. We discovered it also helps cells make and use energy properly. Without AS3MT, cells' mitochondria do not work well, leading to fatty liver and reduced activity. Increasing AS3MT in liver cells restores energy and protects against arsenic damage,
Patrice Delaney   +10 more
wiley   +1 more source

Iloperidone treatment mitigates the Juvenile Huntington's Disease phenotype possibly via Sigma‐1 Receptor Modulation

open access: yesThe FEBS Journal, EarlyView.
We investigated the potential of iloperidone as an activator of Sigma‐1 receptor (S1R) neuroprotective function in juvenile Huntington's disease (jHD). We tested iloperidone on cortical neurons differentiated from patient‐derived iPSCs, demonstrating that it acts as a S1R agonist, decreasing apoptosis, huntingtin aggregation, and oxidative stress ...
Ersilia Fornetti   +11 more
wiley   +1 more source

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