Results 91 to 100 of about 2,908,161 (256)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Abundance [PDF]

Prairie Schooner, 2020
  +7 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Početnosť a rozšírenie kuvika obyčajného (Athene noctua) v Rimavskej kotline (južné Slovensko) / The abundance and distribution of Little Owl (Athene noctua) in Rimavská kotlina Basin (S Slovakia) [PDF]

Tichodroma, 2018
The abundance and distribution of Little Owl was monitored in Rimavská kotlina Basin (central Slovakia) in the years 2015–2017 using visual observations, recording of spontaneous calls and playback of male territorial calls.
Monika GÁLFFYOVÁ
doaj  

Barium abundance in red giants of NGC 6752. Non-local thermodynamic equilibrium and three-dimensional effects

, 2012
(Abridged) Aims: We study the effects related to departures from non-local thermodynamic equilibrium (NLTE) and homogeneity in the atmospheres of red giant stars in Galactic globular cluster NGC 6752, to assess their influence on the formation of Ba II ...
A. Kučinskas, Andrievsky, Asplund, Behara, Bonifacio, Caffau, Caffau, Carretta, Carretta, Carretta, Carretta, Castelli, Cohen, Collet, Collet, Decressin, D’Ercole, E. Caffau, Freytag, González Hernández, Gratton, Gratton, H.-G. Ludwig, Harris, James, Korotin, Korotin, Kraft, Kupka, Kurucz, Ludwig, Mashonkina, Mashonkina, Mashonkina, Mishenina, Norris, Norris, Otsuki, P. Bonifacio, Pasquini, Piotto, Piotto, Ramírez, Roederer, S. A. Korotin, S. M. Andrievsky, Sbordone, Sbordone, Shen, Short, Sneden, Sneden, Sneden, Sobeck, Suntzeff, T. V. Mishenina, V. Dobrovolskas, Yong   +57 more
core   +2 more sources

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Characteristics of phytoplankton in the Zaporizhzhia reservoir for the period of its existence (review)

Ribogospodarsʹka Nauka Ukraïni, 2019
Purpose. Based of literature data, in chronological order, to compose a list of leading scientists who investigated phytoplankton in the middle part of the River Dnipro, which, after the construction of the Dniprostan dam, became the Dnipro (Zaporizhzhia)
O. Fedonenko, Yu. Nikolenko
doaj   +1 more source

Evaluation of climate change scenarios based on aquatic food web modelling [PDF]

, 2008
In the years 2004 and 2005 we collected samples of phytoplankton, zooplankton and macroinvertebrates in an artificial small pond in Budapest. We set up a simulation model predicting the abundance of the cyclopoids, Eudiaptomus zachariasi and Ischnura ...
Hufnagel, Levente, Sipkay, Csaba, Vadadi Fülöp, Cs., Verasztó, Cs.   +3 more
core  

Evidence of Multiple r-Process Sites in the Early Galaxy: New Observations of CS 22892-052

, 2000
First results are reported of a new abundance study of neutron-capture elements in the ultra-metal-poor (UMP; [Fe/H] = -3.1) halo field giant star CS 22892-052.
Christopher Sneden, George M. Fuller, Inese I. Ivans, James E. Lawler, John J. Cowan, Rosswog S., Scott Burles, Timothy C. Beers   +7 more
core   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source