Results 91 to 100 of about 1,660,748 (353)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Absolute isotopic abundance of terrestrial silver

open access: yes, 1962
Isotopic abundance ratios are reported for a commercial silver nitrate, 13 samples of native silver, and 11 silver minerals of various compositions and from widely distributed deposits.
Shields, William R.; Garner, Ernest L.; Dibeler, Vernon H.
core   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Abundance of small individuals influences the effectiveness of processing techniques for deep-sea nematodes

open access: yes, 2010
Nematodes are the most abundant metazoans of deep-sea benthic communities, but knowledge of their distribution is limited relative to larger organisms.
Nodder, Scott D.   +9 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

tedcheese/RSOS-NPAC-abundance: RSOS-NPAC-abundance-v1.0

open access: yes
<p>This archive contains photo-ID data sourced from Happywhale.com and R code for preprocessing and creating abundance estimations</p> <p>Please note data has many copyrights and can only be used for recreation of abundance estimation ...
Ted Cheeseman
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Početnosť a rozšírenie kuvika obyčajného (Athene noctua) v Rimavskej kotline (južné Slovensko) / The abundance and distribution of Little Owl (Athene noctua) in Rimavská kotlina Basin (S Slovakia) [PDF]

open access: yesTichodroma, 2018
The abundance and distribution of Little Owl was monitored in Rimavská kotlina Basin (central Slovakia) in the years 2015–2017 using visual observations, recording of spontaneous calls and playback of male territorial calls.
Monika GÁLFFYOVÁ
doaj  

Estimating bird abundance : making methods work

open access: yes, 2008
In many bird monitoring Surveys, no attempt is made to estimate bird densities or abundance. instead, counts of one form or another are made, and these are assumed to correlate with bird density. Unless complete Counts Oil Sample plots are feasible, this
Marsden, Stuart J.   +2 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Home - About - Disclaimer - Privacy