Results 151 to 160 of about 3,683,011 (357)

Ensamble de crustáceos bentónicos en un lago salino tropical Benthic crustaceans assemblage in a tropical, saline lake

open access: yesRevista Mexicana de Biodiversidad, 2010
El presente trabajo reconoce la composición, estructura y distribución espacial del ensamble de crustáceos bentónicos de Alchichica, un lago salino tropical ubicado en el extremo oriental del altiplano mexicano. El lago presenta una riqueza taxonómica de
Ma. del Carmen Hernández   +2 more
doaj  

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Abundance and Food Preferences of Amphipods (Crustacea: Amphipoda) in the Eastern Gulf of Finland, Baltic Sea [PDF]

open access: yesЖурнал Сибирского федерального университета: Серия Биология, 2016
This paper focuses on the group of the estuarine Baltic amphipods describing abundance and biomass of their representatives in the shallow- and deep water communities of the eastern part of the Gulf of Finland and assessing their food habits.
Nadezhda A. Berezina, Alexey A. Maximov
doaj  

The void abundance with non-gaussian primordial perturbations [PDF]

open access: green, 2009
Marc Kamionkowski   +2 more
openalex   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

The Distribution of Lianas and Their Change in Abundance in Temperate Forests Over the Past 45 Years [PDF]

open access: yes, 2006
Lianas (woody vines) are an important and dynamic component of many forests throughout the world, and increases in CO2, mean winter temperature, and forest fragmentation may promote their growth and proliferation in temperate forests.
Londre, Ronald A., Schnitzer, Stefan A.
core   +1 more source

Bird community in an Araucaria forest fragment in relation to changes in the surrounding landscape in Southern Brazil Comunidade de aves em um fragmento de floresta de araucária em relação a mudanças na paisagem circundante no sul do Brasil

open access: yesIheringia: Série Zoologia, 2012
The dynamics of the bird community in a small forest fragment was evaluated along seven years in relation to changes in the surrounding landscape. The study area is an Araucaria forest fragment in Southern Brazil (state of Paraná).
Pedro Scherer-Neto   +1 more
doaj  

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