Results 171 to 180 of about 3,683,011 (357)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Significant Association Between Increased Abundance of Selected Bacterial Lipopolysaccharides and Norovirus Diarrhea Among South African Infants

Viruses
Bacterial lipopolysaccharides (LPS) have been shown to promote enteric viral infections. This study assessed whether possessing elevated levels of LPS was associated with norovirus infection. Fecal samples from diarrheic norovirus-positive (DNP) (n = 26),
Lerato P. Kgosana, Mapaseka L. Seheri, Cliff A. Magwira   +2 more
doaj   +1 more source

Natural Resource Abundance and Economic Growth

, 1995
J. Sachs, Andrew M. Warner
semanticscholar   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Insights into the regulation of protein abundance from proteomic and transcriptomic analyses

Nature reviews genetics, 2012
C. Vogel, E. Marcotte
semanticscholar   +1 more source

Comparison of Abundance of Premolar and Molar Pulp Stones Before and After Orthodontic Treatment Using Panoramic Radiography

, 2021
Erfaneh Afsari, Elmira Niksolat, Farzaneh Ostovar, Shaghayegh Karimi   +3 more
openalex   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Plastic is in the details: the impact of plastic pollution through a mesocosm experiment

Frontiers in Marine Science
Microbial diversity plays key role in marine ecosystems, and quantifying the impact of plastic pollution on these organisms is essential to better anticipate and manage threats to these fragile ecosystems.
Maeva Goulais, Sophie Darinot-Thomas, Guillaume Mitta, François Galgani, Denis Saulnier, Laura Benestan, Laura Benestan   +6 more
doaj   +1 more source

Using mobile acoustic monitoring and false‐positive N‐mixture models to estimate bat abundance and population trends [PDF]

Bradley J. Udell, Bethany Straw, Susan C. Loeb, Kathryn M. Irvine, Wayne E. Thogmartin, Cori L. Lausen, Jonathan D. Reichard, Jeremy T. H. Coleman, Paul M. Cryan, Winifred F. Frick, Brian E. Reichert   +10 more
openalex   +1 more source