Results 21 to 30 of about 2,332,140 (313)
Nature Communications, 2022 The prefrontal cortex is involved in goal-directed behaviour. Here the authors show that medial prefrontal cortex activates goal-directed motivation and dopamine neurons via a feedback loop with the anteromedial thalamus.
Chen Yang +20 more
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Gs- versus Golf-dependent functional selectivity mediated by the dopamine D1 receptor
Nature Communications, 2018 D1-like dopamine receptors are coupled to Golf proteins in the dorsal striatum but Gs in cortical and other areas. Here, the authors demonstrate selective agonism of Gs-coupled versus Golf-coupled D1 receptors.
Hideaki Yano +9 more
doaj +1 more source
Frontiers in Psychiatry, 2019 Opioid use in the United States has steadily risen since the 1990s, along with staggering increases in addiction and overdose fatalities. With this surge in prescription and illicit opioid abuse, it is paramount to understand the genetic risk factors and
Jamie A. Burns +8 more
doaj +1 more source
The Decline in Child Sexual Abuse Cases. [PDF]
, 2001 Of all crimes against children, sexual abuse has arguably captured the greatest share of attention from child advocates, professionals, policymakers, and the general public.
Finkelhor, David, Jones, Lisa M.
core +2 more sources
Hepatitis Infection in the Treatment of Opioid Dependence and Abuse
Substance Abuse: Research and Treatment, 2008 Many new and existing cases of viral hepatitis infections are related to injection drug use. Transmission of these infections can result directly from the use of injection equipment that is contaminated with blood containing the hepatitis B or C virus or
Thomas F. Kresina +6 more
doaj +1 more source
Trend in alcohol use in Australia over 13 years: has there been a trend reversal?
BMC Public Health, 2016 Background Skog’s collectivity theory of alcohol consumption predicted that changes in alcohol consumption would synchronize across all types of drinkers in a population. The aim of this paper is examine this theory in the Australian context. We examined
Gary C.K. Chan +9 more
doaj +1 more source
Drug-associated cues and drug dosage contribute to increased opioid seeking after abstinence
Scientific Reports, 2021 Patients with opioid use disorder experience high rates of relapse during recovery, despite successful completion of rehabilitation programs. A key factor contributing to this problem is the long-lasting nature of drug-seeking behavior associated with ...
Mary Tresa Zanda +2 more
doaj +1 more source
Psychosis and sexual abuse: an interpretative phenomenological analysis [PDF]
, 2018 This is the peer reviewed version of the following article: J. E. Rhodes, N. D. O’Neill, and P. W. Nel, ‘Psychosis and sexual abuse: An interpretative phenomenological analysis’, Clinical Psychology & Psychotherapy, March 2018, which has been published ...
Arntz +26 more
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4191 The Role of Suggestibility and Trait Anxiety in Young Adult Alcohol Use
Journal of Clinical and Translational Science, 2020 OBJECTIVES/GOALS: The purpose of this study was to investigate how suggestibility and social susceptibility relate to alcohol use in young adult non-dependent alcohol users, and the role of trait anxiety in this relationship. We hypothesized that greater
Alexandra Cowand +6 more
doaj +1 more source
Public spending for illegal drug and alcohol treatment in hospitals: an EU cross-country comparison [PDF]
, 2014 Background: In view of the current economic crisis and the resulting austerity measures being implemented by governments across Europe, public expenditure for substance abuse treatment has increasingly become a subject of discussion.
Christiaens, Johan +2 more
core +3 more sources