Results 71 to 80 of about 17,529 (300)

Abuse of a dominant position

open access: yes, 2013
The aim of competition policy is to prevent companies with a dominant position in their economic sector from abusing this position and from distorting competition in intra-Community trade.
Gild, Yana
core  

ANKS1B in the Nucleus Accumbens Controls Escalated Cocaine Self‐Administration via Regulating CBP‐FoxO3 Complex

open access: yesAdvanced Science, EarlyView.
ANKS1B in the nucleus accumbens plays a critical role in the transition from controlled to escalated cocaine intake. Mechanistically, ANKS1B interacts with CBP to epigenetically suppress FoxO3 through H3K27 acetylation. The ANKS1B‐CBP‐FoxO3 signaling cascade presents a novel theraputic target for the treatment of cocaine addiction.
Liping Yang   +15 more
wiley   +1 more source

Intersection between the activities of two regulators – shall prior actions taken by the National Telecoms Regulator exclude the ability to intervene by the Competition Authority?Case comments to the judgment of the Supreme Court of 17 March 2010 –Telekomunikacja Polska S.A. (Ref. No. III SK 41/09) [PDF]

open access: yesYearbook of Antitrust and Regulatory Studies, 2011
The commented judgment of the Polish Supreme Court concerns Telekomunikacja Polska S.A. (hereafter, TPSA) and the fines imposed upon the incumbent operator by the President of the Office of Competition and Consumer Protection (in Polish: Urząd Ochrony ...
Szymon Syp
doaj  

Isosteric Substitution Enables Rational Design of Two‐Dimensional Energetic Crystals

open access: yesAdvanced Science, EarlyView.
Isosteric substitution transforms a classical nitro–amine motif into two‐dimensional aminofurazans with performance beyond TATB. ABSTRACT Two‐dimensional (2D) energetic crystals dissipate mechanical insult via interlayer slip, yet their molecular design space remains narrow.
Linyuan Wen   +6 more
wiley   +1 more source

Fosl2 Regulates FSH‐Dependent Follicle Maturation Through Feedback Amplification of FSH/FSHR Signaling

open access: yesAdvanced Science, EarlyView.
This study identifies a FOSL2‐driven positive feedback loop that amplifies FSH/FSHR signaling. During FSH‐dependent follicle maturation, FSH induces Fosl2 expression via the cAMP‐PKA‐CREB cascade. FOSL2 in turn binds the promoters of Fshr and estrogen‐biosynthesis genes to enhance their transcription, thereby increasing Fshr mRNA level and amplifying ...
Hongru Shi   +13 more
wiley   +1 more source

PREVENTING THE ABUSE OF MONOPOLY (DOMINANT) POSITION

open access: yes, 2016
This article studies the dynamics of abuse of monopoly (dominant) position. Economic and legal means of preventing abuse of monopoly (dominant) position have been justified.
Грудницький, Василь Миколайович
core  

A Portable and Dual‐Button Microneedle Device Enables Intelligent Multimodal Laser Sensing

open access: yesAdvanced Science, EarlyView.
A portable and dual‐button microneedle device enables rapid interstitial fluid sampling. Coupled with multimodal laser sensing and AI‐assisted data processing, the platform enables simultaneous molecular and elemental analysis for minimally invasive and multiplexed health assessment toward point‐of‐care diagnostics.
Yuanchao Liu   +12 more
wiley   +1 more source

Oxygen Vacancy‐Enriched Platinum Single‐Atom Nanozyme Wrapped in Nanoislands: Unlocking Catalytic Activity and Reprogramming Redox Microenvironment for Osteonecrosis Repair

open access: yesAdvanced Science, EarlyView.
CeO2‐x/Pt single‐atom nano‐island is constructed via low‐temperature reduction, featuring abundant oxygen vacancies and an island–sea structure. It delivers outstanding multi‐enzyme‐mimetic activity and ROS‐scavenging efficiency. Density functional theory reveals optimized electronic structures and reaction pathways.
Yang Zhu   +12 more
wiley   +1 more source

Rola dużych danych w ocenie nadużycia pozycji dominującej przez platformy internetowe oparte na danych w unijnym prawie konkurencji

open access: yes, 2020
The main research objective of the dissertation is to analyse whether and if so, how the EU legal framework for the assessment of abuse of a dominant position under Article 102 TFEU15 should be adjusted to address the competition online platforms and, if
Małobęcka-Szwast, Iga
core  

Single‐Cell Annotation and Localization via Integrating Spatial Transcriptomics Maps the Mouse Ocular Atlas and RAO Dynamics

open access: yesAdvanced Science, EarlyView.
We developed the ASCAL pipeline, integrating complementary spatial transcriptomics, to construct a high‐fidelity mouse whole‐eye single‐cell atlas. Applying ASCAL to a retinal artery occlusion (RAO) model revealed spatially restricted immune activation localized to the ganglion cell layer and the selective depletion of a translationally active, outer ...
Chen Du   +11 more
wiley   +1 more source

Home - About - Disclaimer - Privacy