Results 91 to 100 of about 4,918 (294)

Chat Control and the Repercussions of Mandatory Communication Detection

Trento Student Law Review
This article analyses the European Union’s proposed Child Sexual Abuse Regulation (“Chat Control”) and the legal, technical, and fundamental-rights challenges arising from its shift from voluntary to mandatory detection of online child sexual abuse ...
Mariavittoria Scarsini
doaj   +1 more source

Optical Windows for Transcranial Brain Imaging in Living Mice: Skull Thinning, Clearing, and Beyond

Advanced Science, EarlyView.
Longitudinal, noninvasive in vivo imaging is crucial for studying brain physiology. Advances in transcranial optical windows and multiphoton microscopy have improved imaging depth, but their performance often deteriorates over time. This work investigated various transcranial window approaches and found that skull regrowth limits image quality.
Yiming Fu, Gewei Yan, Zhentao She, Yingzhu He, Kangqi Liu, Jianan Qu   +5 more
wiley   +1 more source

Abuso nel diritto civile e nel diritto tributario, e l’abuso del processo – Parte Prima

Aequitas Magazine
This study succinctly illustrates the concept of abuse of rights within civil and tax law, with an evolutionary reconstruction from its origins to recent applications in procedural law, where it has assumed a well-defined position with a regulatory ...
Luigi Di Prisco
doaj  

Lactate‐Driven Restriction of Mitochondrial Permeability Transition Promotes Resistance to Chemo‐Immunotherapy by Suppressing Tumor PANoptosis

Advanced Science, EarlyView.
Tumor‐derived lactate establishes a metabolic lock that drives chemo‐immunotherapy resistance by suppressing PANoptosis. Mechanistically, KAT8 lactylates the mitochondrial translocator ANT2, which recruits PGAM5 to dephosphorylate CypD. This cascade restricts mitochondrial permeability transition pore opening, preventing pro‐inflammatory mtDNA leakage.
Sen Zhong, Wenlong Chen, Fanglong Liu, Shengyi Zhou, Bolin Yu, Yuying Wang, Xiqian Zhou, Xuehui Wang, Diya Liu, Zhuoyu Zhang, Xinran Wang, Mounia Lalouly, Yiwen Li, Zhefei Du, Tao Yan, Zhihui Xiao, Zhou Zhou, Huanhuan Zhu, Fengyuan Qian, Bowen Zheng, Lin Fang   +20 more
wiley   +1 more source

Understanding abuse of rights in the legal positions of the Supreme Court’s Grand Chamber

Розглянуто основні загальнотеоретичні конструкцій щодо розуміння «зловживання процесуальними правами». Наголошено, що зловживання процесуальними правами має тісний зв’язок із зловживаннями матеріальними правами, що має свій прояв у дотриманні загальних ...
Ксенія Гуртова, Гуртова, К. М., Hurtova, K. M.   +2 more
core   +1 more source

THE INCIDENCE OF THE PRINCIPLE OF PROPORTIONALITY IN THE CASE OF PRECAUTIONARY MEASURES ORDERED IN THE ROMANIAN CRIMINAL PROCESS [PDF]

Challenges of the Knowledge Society
The object of the analysed topic deals with the limits and incidence of the criterion of proportionality in taking, maintaining or terminating insurance measures, offering several procedural remedies.
Alina ANDRESCU
doaj  

S100A8/A9‐High Macrophages Activate Intestinal Fibroblasts via mCCL6/hCCL15‐CCR1 Axis to Drive Intestinal Fibrosis in Crohn's Disease

Advanced Science, EarlyView.
S100A8/A9‐high macrophages are markedly enriched in the stenotic intestinal tissue of patients with Crohn's disease. These profibrotic macrophages secrete mCCL6 in a STAT3‐dependent manner. mCCL6 and its human ortholog hCCL15 activate fibroblasts via the CCR1 receptor, thereby driving excessive collagen deposition.
Shu Wang, Jiayun Wang, Junjie Lin, Ziping Ye, Geyujia Zhou, Jingjing Ma, Junjian Sun, Jiang Yu, Yingdi Zhang, Nana Tang, Chunhua Jiao, Xiaojing Zhao, Hongjie Zhang   +12 more
wiley   +1 more source

Fatty Acid Binding Protein 5 Mediates Astrocytic Pyroptosis and Neuroinflammation in Epilepsy via cGAS/STING Pathway

Advanced Science, EarlyView.
Astrocytic FABP5 promotes mitochondrial stress, cGAS‐STING pathway activation, pyroptosis, and neuroinflammation in epilepsy, contributing to seizure pathology. Genetic targeting of FABP5 or pharmacological inhibition of STING alleviates epileptic phenotypes, highlighting a potential therapeutic strategy for epilepsy.
Chen Chen, Yao Zhao, Yangye Lian, Yifei Hou, Lifen Gong, Tingting Wu, Yulin Yang, Jiaqi Zhu, Xin Wang, Kaihua Zhang, Jing Ding   +10 more
wiley   +1 more source

ABUSE OF RIGHTS IN INTERNATIONAL ARBITRATION [PDF]

, 2018
PhDWhile international arbitration offers the prominent scheme for resolution of transnational disputes, the arbitration community must constantly examine areas of concern. Any system of justice, including the arbitration system, is not meant for abuse.
El Far, Ahmed Mohsen
core  

Procedural fairness generally

, 2013
Legal rights and interests are protected in myriad ways and not always in a substantive sense or through entrenched constitutional provisions designed to prescribe or limit power.
Boyron, Sophie, Lacey, Wendy
core   +2 more sources