Results 91 to 100 of about 4,100 (253)

EMPIRICAL ANALYSIS OF FACTORS INFLUENCING THE GRANTING OF PRELIMINARY INJUNCTIONS IN PERNAMBUCO'S FEDERAL COURT

open access: yesRevista de Ciências Jurídicas e Sociais da UNIPAR
What does influence the issuance of Preliminary Injunctions (in limine) in Writs of Mandamus within the jurisdiction of Pernambuco's Federal Court?
Renan Francelino Silva   +3 more
doaj   +1 more source

LEGAL LIABILITY CONDITIONS FOR THE ABUSE OF LAW [PDF]

open access: yesChallenges of the Knowledge Society, 2014
Knowing that in more and more cases, the only defence of the party whose law or interest has been injured is to invoke the abuse of law, the express interdiction of the abuse of law becomes a need as an answer to the social demand for legality and ...
Emilian CIONGARU
doaj  

Cobalt Single‐Atom Nanozyme for Enhanced Intestinal Radioprotection and Tumor Radiosensitization via Bidirectional ROS Modulation

open access: yesAdvanced Science, EarlyView.
Orally administered, pH‐responsive Co‐SAN exerts dual functions: in the alkaline intestinal milieu, it scavenges reactive oxygen species (ROS) and suppresses the PI3K/AKT pathway and NETs formation, thus providing radioprotection; whereas in the acidic tumor microenvironment, it generates ROS and alleviates hypoxia, thereby enhancing radiosensitization.
Shengqi Yin   +13 more
wiley   +1 more source

A Novel IDO1/NE Dual Inhibitor, IMM‐H018 Prevents the Primary and Secondary Sepsis and Ameliorates the Kidney Injury Through Inhibiting the Cytokine Storm and Microthrombosis, and Reversing Immunosuppression

open access: yesAdvanced Science, EarlyView.
IMM‐H018, a dual IDO1/NE inhibitor, demonstrates potent therapeutic efficacy in sepsis by simultaneously targeting excessive inflammation and immune dysfunction. It prevents both primary and secondary sepsis through anti‐inflammatory, immune‐restoring, and renoprotective mechanisms, reducing organ damage, improving immune homeostasis, preserving kidney
Yi Zhou   +11 more
wiley   +1 more source

Effectiveness of prior consultation on the environmental licensing process in the department of Chocó 2006-2011

open access: yesCivilizar, 2014
The Department of Chocó is a “territory with an incalculable natural, ethnic and cultural wealth” (¿Qué es él Chocó Biogeográfico?, 2013); Prior consultation is a right and a mechanism involving ethnic groups, however, is not effective, or is an ...
Marisela Mena Valencia   +1 more
doaj  

Maslahah-Based Judicial Reasoning in Isbat Nikah Cases: Reconciling Legal Certainty and Substantive Justice in the Makassar Religious Court

open access: yesAl-Adalah
The tension between statutory marriage registration requirements and the socio-religious legitimacy of nikah siri (unregistered marriages) continues to create challenges in the implementation of family law in Indonesia.
Siti Nur Fajriyati   +2 more
doaj   +1 more source

Chemoselective Metabolomics via a Modular Reactivity‐Encoding Platform

open access: yesAdvanced Science, EarlyView.
Conventional LC–MS underrepresents numerous metabolites due to heterogeneous ionization efficiencies and matrix interference. Here, we introduce a modular reactivity‐encoding platform (MREP) comprising four alkyne‐tagged probes that selectively derivatize key functional groups, followed by unified click‐chemistry capture to eliminate matrix components ...
Xin Tao   +10 more
wiley   +1 more source

A Second Pathogenic Protein, PolyGN2C‐iso2, Reveals a Dual‐Protein Pathology in Neuronal Intranuclear Inclusion Disease

open access: yesAdvanced Science, EarlyView.
This study reveals that NOTCH2NLC transcript variant 2 generates PolyGN2C‐iso2, an aggregating protein present within intranuclear inclusions of NIID patient tissues. A novel mouse model expressing PolyGN2C‐iso2 recapitulates white matter abnormalities and cognitive deficits, mechanistically linked to mitochondrial dysfunction. These findings support a
Kang Zhang   +22 more
wiley   +1 more source

Human Dental Pulp Stem Cell Secretome Restores Ischemic Stroke–Impaired Motor and Cognitive Functions by Reprogramming Redox and Inflammatory Signaling

open access: yesAdvanced Science, EarlyView.
Human dental pulp stem cell secretome emerges as a cell‐free therapeutic strategy for ischemic stroke by reprogramming redox and inflammatory signaling. hDPSC secretome‐derived antioxidant and immunomodulatory factors suppress the TLR4–NOX–ROS–NF‐κB axis, reduce microglial inflammatory responses and apoptosis, and promote neurogenesis, angiogenesis ...
Kyung‐Joo Seong   +8 more
wiley   +1 more source

Abuse of procedural rights by participants in civil proceedings

open access: yesAktual’ni problemi pravoznavstva, 2023
Nataliia Bachynska, Nadiia Sampara
openaire   +1 more source

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