Results 131 to 140 of about 1,243,573 (351)

Palmitoylation‐Mediated Ubiquitination of SRPK1 Regulates Ferroptosis in High‐Fat‐Induced Erectile Dysfunction

open access: yesAdvanced Science, EarlyView.
Elevated exogenous palmitic acid promotes the S‐palmitoylation of SRPK1 in endothelial cells, a dynamic process governed by ZDHHC24 and APT1. This post‐translational modification strengthens the interaction between SRPK1 and the E3 ubiquitin ligase MIB1, thereby facilitating the proteasomal degradation of SRPK1.
Xiao‐Hui Tan   +11 more
wiley   +1 more source

Concept and legal consequences of abuse of labor law

open access: yesЮридический вестник Самарского университета
Since the current labor legislation of many countries, including Russia, does not contain an unambiguous definition and direct regulation of the abuse of law in labor relations, the work suggests an understanding of the abuse of law in the field of labor
M. N. Bronnikova, S. V. Osipova
doaj   +1 more source

Abuse of Rights in International Arbitration [PDF]

open access: yes, 2020
Abstract In recent years, international arbitration has become plagued by different forms of substantive and procedural abuse. For example, we have witnessed a rise in cases where parties restructure their investments in an abusive manner by altering one of its features purely to gain access to ICSID arbitration.
openaire   +1 more source

Administrative Inconvenience and the Media\u27s Right to Copy Judicial Records [PDF]

open access: yes, 2003
English and American common law have long recognized the public\u27s right of access to judicial records. The United States Supreme Court has acknowledged the importance of this right but has failed to set clear standards for lower courts to follow in ...
Coffey, Melissa B
core  

Coincident Fluorescence‐Burst Analysis of Actin Cargo Molecules in Secreted Single Diffusing Extracellular Vesicles From Human Induced Pluripotent Stem Cells

open access: yesAdvanced Science, EarlyView.
This study presents a two‐color FCCS and coincident‐burst analysis platform to quantify actin cargo in dual‐labeled EVs secreted from hiPSCs. The approach tracks secretion dynamics, confirms actin loading, and measures EV size and cargo number, offering insights into cytoskeletal disruption and neuronal differentiation relevant to neurodegenerative ...
Dang Du Nguyen   +4 more
wiley   +1 more source

Dissociative experiences alter resting state functional connectivity after childhood abuse

open access: yesScientific Reports
Dissociative experiences commonly occur alongside adverse childhood experiences (ACE), yet research on their neurofunctional biomarkers has overlooked their unique association with dimensions of childhood abuse and neglect.
Claudius von Schröder   +4 more
doaj   +1 more source

The Spiral of Risk: Health Care Provision to Incarcerated Women [PDF]

open access: yes, 2006
By law, prisoners in the United States have a fundamental right to receive adequate health care. However, most prisoners in this nation face numerous obstacles when attempting to receive quality health services.

core  

PRDM1+ Malignant Cells Mediate an Immunosuppressive Landscape and Resistance to Neoadjuvant Chemoradiotherapy and Immunotherapy in Esophageal Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
Integrated scRNA‐seq, scTCR‐seq analysis, and functional assays identify PRDM1+ malignant epithelial cells with hyper lipid peroxidation characteristics that demonstrate reduced responsiveness to the nICRT treatment. Principal factor PRDM1 activates cysteine metabolism genes to modulate lipid peroxidation (an intrinsic cellular pathway related to ...
Dijian Shen   +12 more
wiley   +1 more source

Kebijakan Pemerintah Daerah dalam Menertibkan Peredaran Minuman Keras di Kota Cilegon Provinsi Banten [PDF]

open access: yes, 2012
Product of local government is needed to regulate various aspects in a area, especially in regulating the distribution of alcohol. While, Cilegon a pluralistic society because it is a gateway island of Java-sumatera, so it takes the right product from ...
Amiruddin, S. (Suwaib)
core  

TP53BP2 Promotes Placental Autophagy and Preeclampsia via G9a and DNMT1 Cooperatively Modulating E2F1

open access: yesAdvanced Science, EarlyView.
G9a, and DNA Methyltransferase1 (DNMT1) cooperatively modulates E2F1 on the promoter of tumor suppressor p53‐binding protein 2 (TP53BP2) increased autophagy in preeclampsia. TP53BP2 promotes autophagy in trophoblasts through DNA methylation and H3K9me2‐mediated transcriptional regulation.
Nan Jiang   +12 more
wiley   +1 more source

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