Results 111 to 120 of about 936,114 (310)
Advanced Science, EarlyView.Elevated exogenous palmitic acid promotes the S‐palmitoylation of SRPK1 in endothelial cells, a dynamic process governed by ZDHHC24 and APT1. This post‐translational modification strengthens the interaction between SRPK1 and the E3 ubiquitin ligase MIB1, thereby facilitating the proteasomal degradation of SRPK1.
Xiao‐Hui Tan +11 more
wiley +1 more source
Abuse of Rights in International Arbitration [PDF]
, 2020 Abstract In recent years, international arbitration has become plagued by different forms of substantive and procedural abuse. For example, we have witnessed a rise in cases where parties restructure their investments in an abusive manner by altering one of its features purely to gain access to ICSID arbitration.
openaire +1 more source
The Status of Women in the South [PDF]
, 2016 The southern United States is a dynamic and influential region marked by innovation and economic opportunities for women, yet also a region where inequalities persist and many women -- especially women of color and those who are immigrants -- face ...
Asha DuMonthier +4 more
core
Advanced Science, EarlyView.This study presents a two‐color FCCS and coincident‐burst analysis platform to quantify actin cargo in dual‐labeled EVs secreted from hiPSCs. The approach tracks secretion dynamics, confirms actin loading, and measures EV size and cargo number, offering insights into cytoskeletal disruption and neuronal differentiation relevant to neurodegenerative ...
Dang Du Nguyen +4 more
wiley +1 more source
Localizing Child Protection: Does the Local Council for the Protection of Children Matter? [PDF]
Child protection pertains to “preventing and responding to violence, exploitation, and abuse against children.” More specifically, it encompasses all processes, policies, programs, interventions, and measures that aim to prevent and respond to violence ...
Cuenca, Janet S.
core
Conditioning U.S. Security Assistance on Human Rights Practices [PDF]
, 1982 In the United States, with its government of separated powers and functions, it is the executive branch, and in particular the Department of State, that bears responsibility for implementing legislation on foreign relations. The success of implementation
Cohen, Stephen B.
core +1 more source
Advanced Science, EarlyView.Integrated scRNA‐seq, scTCR‐seq analysis, and functional assays identify PRDM1+ malignant epithelial cells with hyper lipid peroxidation characteristics that demonstrate reduced responsiveness to the nICRT treatment. Principal factor PRDM1 activates cysteine metabolism genes to modulate lipid peroxidation (an intrinsic cellular pathway related to ...
Dijian Shen +12 more
wiley +1 more source
Asylum in Practice: Successes, Failures, and the Challenges Ahead [PDF]
, 2000 The Workshop on Refugee and Asylum Policy in Practice in Europe and North America was organized to facilitate a transatlantic dialogue aimed at understanding just how well these asylum systems are balancing the dual goals.
Martin, Susan, Schoenholtz, Andrew I.
core +1 more source
Advanced Science, EarlyView.G9a, and DNA Methyltransferase1 (DNMT1) cooperatively modulates E2F1 on the promoter of tumor suppressor p53‐binding protein 2 (TP53BP2) increased autophagy in preeclampsia. TP53BP2 promotes autophagy in trophoblasts through DNA methylation and H3K9me2‐mediated transcriptional regulation.
Nan Jiang +12 more
wiley +1 more source
Advanced Science, EarlyView.The diagram depicts the endothelial‐protective mechanism of magnesium lithospermate B (MLB) in sepsis‐associated lung injury. MLB binds GPX4 at Gly79, disrupts its interaction with FUNDC1, prevents mitophagy‐mediated GPX4 degradation, restores mitophagic flux, reduces ROS, and limits ferroptosis.
Zhixi Li +10 more
wiley +1 more source