Results 91 to 100 of about 2,252,616 (352)

Onasemnogene Abeparvovec in Type I Spinal Muscular Atrophy: 24‐Month Follow‐Up From the Italian Registry

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane   +43 more
wiley   +1 more source

MMC with parallel-connected MOSFETs as an alternative to wide bandgap converters for LVDC distribution networks

open access: yesThe Journal of Engineering, 2017
Low-voltage direct-current (LVDC) networks offer improved conductor utilisation on existing infrastructure and reduced conversion stages, which can lead to a simpler and more efficient distribution network. However, LVDC networks must continue to support
Yanni Zhong   +4 more
doaj   +1 more source

Vegetable Fertility Management Trial [PDF]

open access: yes, 2016
Many organic vegetable producers have been relying heavily on livestock composts as a source of fertility on farms. Often, high rates of compost are applied to meet the nitrogen (N) needs of crops.
Cubins, Julija   +4 more
core   +2 more sources

Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold   +12 more
wiley   +1 more source

Loss of adaptive capacity in asthmatic patients revealed by biomarker fluctuation dynamics after rhinovirus challenge

open access: yeseLife, 2019
Asthma is a dynamic disease, in which lung mechanical and inflammatory processes interact in a complex manner, often resulting in exaggerated physiological, in particular, inflammatory responses to exogenous triggers.
Anirban Sinha   +7 more
doaj   +1 more source

Safety and Tolerability of Givinostat: Evidence From Real‐World and Clinical Practice

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The aim of our study was to establish the prevalence of adverse events in a real‐world setting in boys living with Duchenne muscular dystrophy (DMD) treated with givinostat as part of an Expanded Access Program (EAP) in Italy. Methods The cohort included 90 ambulant boys, with age when treatment started between 6 and 23 years (mean ...
Marika Pane   +19 more
wiley   +1 more source

Estimation of AC loss in cylindrical superconductor with ripple current [PDF]

open access: yes, 2012
The loss energy density (AC loss) in cylindrical superconductor with ripple current based on Irie-Yamafuji model in which the magnetic fiel dependence of critical current density is taken into account is theoretically calculated for design of DC ...
Kawahara T.   +4 more
core   +2 more sources

MOGAD Is the Most Common Cause of Isolated Optic Neuritis in Children

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives The study aimed to characterize the clinical features, etiologies, and outcomes of isolated, first‐time pediatric ON in the post‐MOG‐IgG era. Methods This was a single‐center retrospective cohort study at Texas Children's Hospital of patients diagnosed with first‐time ON between 2018–2024, with follow‐up data collected through 2025.
Chaitanya Aduru   +13 more
wiley   +1 more source

Treatment of Type V Acromioclavicular Separation with Minimally Invasive Closed-loop Double-endobutton Technique

open access: yesFormosan Journal of Musculoskeletal Disorders
Background: Acromioclavicular (AC) separation is a prevalent shoulder girdle injury, accounting for 50% of all sports-related shoulder injuries. Surgery is recommended for Rockwood Types IV-VI injuries.
Wei-Hsiang Yang   +3 more
doaj   +1 more source

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