Results 81 to 90 of about 2,239,837 (306)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Coordinated control of power loss and capacitor voltage ripple reduction for AC voltage boosted FBSM MMC with second harmonic circulating current injection

open access: yesHigh Voltage, 2018
Reducing the converter loss, sub-module voltage ripple and handling DC short-circuit faults in high-voltage direct current systems are crucial for the economical and reliable operation of modular multilevel converters (MMCs).
Muchao Xiang   +3 more
doaj   +1 more source

Computation of AC loss of HTS coils wound by coated conductors with different widths

open access: yesAIP Advances, 2022
The second-generation high-temperature superconductor (HTS) tape is a promising material for the HTS application. However, the extremely large aspect ratio of the HTS coated tape leads to high power dissipation in the environment of a time-varying ...
Liuyuan Yu, Huadong Yong
doaj   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

The effects of financial incentives on diabetes prevention program attendance and weight loss among low-income patients: the We Can Prevent Diabetes cluster-randomized controlled trial

open access: yesBMC Public Health, 2020
Background Penetration and participation of real life implementation of lifestyle change programs to prevent type 2 diabetes has been challenging. This is particularly so among low income individuals in the United States.
Jay R. Desai   +11 more
doaj   +1 more source

Effect of combining a DC bias current with an AC transport current on AC losses in a High Temperature Superconductor

open access: yes, 1998
Creating complex flux configurations by superposing a dc current or magnetic field onto the ac current in a type II superconducting tape should lead to a variety of peculiar behaviors.
Aubin, Marcel   +4 more
core   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Effects of a novel peptide Ac-SDKP in radiation-induced coronary endothelial damage and resting myocardial blood flow

open access: yesCardio-Oncology, 2018
Background Cancer survivors treated with thoracic ionizing radiation are at higher risk of premature death due to myocardial ischemia. No therapy is currently available to prevent or mitigate these effects.
Umesh C. Sharma   +11 more
doaj   +1 more source

Soil corrosion of the AISI1020 steel buried near electrical power transmission line towers [PDF]

open access: yesMaterials Research, 2014
Soil corrosion of carbon steel samples buried up to hundred days close to a high voltage power transmission line tower was examined by weight loss vs. time. A higher weight loss was observed if the samples were electrically connected to the tower than if
Anderson de Oliveira Fraga   +5 more
doaj   +2 more sources

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

open access: yesFEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz   +9 more
wiley   +1 more source

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