Results 61 to 70 of about 3,578,639 (293)

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Speed Control of an Induction Motor Fed by an Inverter Using dSPACE Controller [PDF]

open access: yesE3S Web of Conferences, 2019
This paper presents the design and implementation of Inverter system for driving three phase Induction motor using DSPACE DS1104 controller with the controlling objective space vector pulse width modulation (SVPWM) technique. AC motor drives are commonly
Janiga Srinivasrao   +3 more
doaj   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

РОЗВИТОК ТЕОРІЇ ВЕКТОРНОГО КЕРУВАННЯ АСИНХРОННИМИ ДВИГУНАМИ НА ОСНОВІ ДЕКОМПОЗИЦІЇ «МЕХАНІЧНА ‒ ЕЛЕКТРИЧНА ПІДСИСТЕМИ»

open access: yesПраці Інституту електродинаміки Національної академії наук України
The theory of field-oriented control of induction motors, which emerged in the early 2000s, is based on a fundamental property of field orientation, which involves decomposing the motor’s output into two independent subsystems: electro-mechanical and ...
С.М. Пересада   +2 more
doaj   +1 more source

Kendali Motor Induksi 3 Fasa Menggunakan Arduino Mega Berbasis HMI (Human Machine Interface)

open access: yesJurnal Teknik Elektro Indonesia, 2020
Motor induksi 3 Fasa merupakan jenis motor yang paling banyak digunakan untuk menggerakan berbagai beban/mesin. Dalam instalasinya, motor induksi 3 fasa dengan daya besar memerlukan rangkaian starting dan kendalinya seperti untuk membalik arah putaran ...
Eni Mariani Mariani, Hastuti hastuti
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Speed Control of DC Motor using AC/AC/DC Converter Based on Intelligent Techniques

open access: yesTikrit Journal of Engineering Sciences, 2013
   This paper describes the application of ac/ac/dc and ac/dc converters to control the speed of a separately excited DC motor. Artificial neural network and PI controller are trained to select the desired values of firing angles for triggering ...
Rakan Kh Antar
doaj  

Direct torque control for dual three-phase induction motor drives [PDF]

open access: yes, 2004
A direct torque control (DTC) strategy for dual three-phase induction motor drives is discussed in this paper. The induction machine has two sets of stator three-phase windings spatially shifted by 30 electrical degrees.
Profumo, Francesco   +10 more
core   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

open access: yesFEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy