Results 51 to 60 of about 9,074 (311)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Computation of the voltage-driven flux-MMF diagram for saturated PM brushless motors [PDF]

open access: yes, 2005
The flux-MMF diagram or "energy conversion loop" is a powerful tool for computing the average torque of saturated permanent-magnet brushless motors, especially when the assumptions underlying classical dq theory are violated, as they often are in modern ...
McGilp, M.I.   +3 more
core  

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Commutation of permanent-magnet synchronous AC motors for military and traction applications [PDF]

open access: yes, 2003
The permanent-magnet ac (PMAC) motor requires accurate position information to be supplied to the controller so that the applied currents can be modulated in synchronism with the rotor.
Stewart, Paul, Kadirkamanathan, Visakan
core   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Induction Motor Supplied with Voltage Containing Symmetrical Subharmonics and Interharmonics

open access: yesEnergies, 2022
Sinusoidal voltage fluctuations can be considered a specific result of the occurrence of voltage subharmonics and interharmonics, which are components of low frequency or not being an integer multiple of the frequency of the fundamental voltage harmonic.
Piotr Gnaciński   +4 more
doaj   +1 more source

Effect of winding harmonics on the asynchronous torque of a single-phase line start permanant-magnet motor [PDF]

open access: yes, 2005
This paper presents an analytical method for calculating the effect of winding harmonics on the asynchronous torque of a single-phase line-start permanent-magnet motor.
McGilp, M.I.   +11 more
core   +1 more source

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Speed Control of AC Motor

open access: yesInternational Journal of Innovative Technology and Exploring Engineering, 2020
An enormous number of motors have been using in our daily life ranging from home appliances to industrial machinery. During the last decade, there has been tremendous change industry automation and home automation. Electric motor is always the essential part in home appliances as well as industrial applications in the automation. There is always a need
Y. Sudha*, P. Pooja, K Rama, P. Shweta
openaire   +1 more source

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