Results 81 to 90 of about 104,240 (279)

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende   +26 more
wiley   +1 more source

Vivendo em Manguinhos: a trajetória de um grupo de cientistas no Instituto Oswaldo Cruz

open access: yesHistória, Ciências, Saúde: Manguinhos, 2001
Este artigo analisa a trajetória de um grupo de cientistas biomédicos de Manguinhos, centrando-se no processo de construção de suas carreiras profissionais, entre as décadas de 1920 e 1950.
Calaça Carlos Eduardo
doaj  

Innovación militar en la España del siglo XVIII: la producción científica de la Real Escuela Militar de Ávila (1774)

open access: yesCuadernos de Historia Moderna, 2016
La Real Escuela Militar de Ávila fue, probablemente, la academia militar más original del siglo XVIII en España. Esta contribución analiza el trabajo de producción científica llevado a cabo desde su apertura en 1774 hasta su cierre en 1779.
Óscar Recio Morales
doaj   +1 more source

A formacao da cultura jurídica nacional e os cursos jurídicos no brasil: uma análise preliminar (1854-1879) [PDF]

open access: yes, 2005
Este trabajo pretender detectar las características de la formación de la cultura jurídica brasileña en la segunda mitad del siglo XIX. Considerando el esfuerzo realizado por Brasil nada más independizarse por formar sus propios cuadros culturales ...
Fonseca, Ricardo Marcelo
core   +1 more source

El web marketing en la difusión del DELE [PDF]

open access: yes, 2013
En el último siglo, internet ha supuesto una herramienta que ha revolucionado la sociedad, y dentro de esta revolución, el marketing ha supuesto un paso más. El mundode la enseñanza, y en concreto el DELE, no ha quedado exento de esta influencia. De esta
Giménez Folqués, David
core   +4 more sources

Feasibility and Tolerability of Performing Portable MRI for Neurological Disorders in an Outpatient Neurology Clinic: A Prospective Cohort

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Accessing brain magnetic resonance imaging (MRI) can be challenging, especially for underserved patients, which may lead to disparities in neurological diagnosis. Method This mixed‐methods study enrolled adults with one of four neurological disorders: mild cognitive impairment or dementia of the Alzheimer type, multiple sclerosis ...
Maya L. Mastick   +19 more
wiley   +1 more source

Development of a Personalized Visualization and Analysis Tool to Improve Clinical Care in Complex Multisystem Diseases With Application to Scleroderma

open access: yesArthritis Care &Research, EarlyView.
Objective In complex diseases, it is challenging to assess a patient's disease state, trajectory, treatment exposures, and risk of multiple outcomes simultaneously, efficiently, and at the point of care. Methods We developed an interactive patient‐level data visualization and analysis tool (VAT) that automates illustration of the trajectory of a ...
Ji Soo Kim   +18 more
wiley   +1 more source

Hydroxychloroquine Associated With Lower Glomerular Filtration Rate Decline in Lupus Nephritis

open access: yesArthritis Care &Research, EarlyView.
Objective Hydroxychloroquine (HCQ) protects kidney function in lupus nephritis (LN) by preventing flares, yet some cohort studies show no significant benefit in kidney function with HCQ. Clarifying these conflicting findings by showing early and long‐term benefits of HCQ on kidney function preservation is critical.
Shivani Garg   +9 more
wiley   +1 more source

Tándem [PDF]

open access: yes, 2016
La finalidad de Tándem es poder realizar un modelo de negocio centrado en ofrecer una solución a diferentes usuarios que quieran aprender idiomas vía online en cualquier parte del mundo. El objetivo es crear una plataforma online totalmente gratuita para
Batista Perez, Juan   +1 more
core  

Improvements in Health‐Related Quality of Life With Treat‐to‐Target Urate‐Lowering Therapy in Gout: A Post Hoc Analysis of a Randomized Multicenter Trial

open access: yesArthritis Care &Research, EarlyView.
Objective Although treat‐to‐target urate‐lowering therapy (ULT) is endorsed as best practice in gout management, limited data exist on its impact on health‐related quality of life (HRQoL). We assessed the impact of treat‐to‐target ULT on HRQoL among participants receiving protocolized gout care, identifying factors associated with HRQoL and HRQoL ...
Austin Barry   +16 more
wiley   +1 more source

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