Results 51 to 60 of about 172 (166)

Loss of hepatic SMLR1 causes hepatosteatosis and protects against atherosclerosis due to decreased hepatic VLDL secretion

Hepatology, EarlyView., 2022
The role of SMLR1 in lipid metabolism (high fat + cholesterol diet in mice) Abstract Background and Aims The assembly and secretion of VLDL from the liver, a pathway that affects hepatic and plasma lipids, remains incompletely understood. We set out to identify players in the VLDL biogenesis pathway by identifying genes that are co‐expressed with the ...
Willemien van Zwol, Antoine Rimbert, Justina C. Wolters, Marieke Smit, Vincent W. Bloks, Niels J. Kloosterhuis, Nicolette C. A. Huijkman, Mirjam H. Koster, Umesh Tharehalli, Simon M. de Neck, Colin Bournez, Marceline M. Fuh, Jeroen Kuipers, Sujith Rajan, Alain de Bruin, Henry N. Ginsberg, Gerard J. P. van Westen, M. Mahmood Hussain, Ludger Scheja, Joerg Heeren, Philip Zimmerman, Bart van de Sluis, Jan Albert Kuivenhoven   +22 more
wiley   +1 more source

Health disparities in chronic liver disease

Hepatology, EarlyView., 2022
Abstract The syndemic of hazardous alcohol consumption, opioid use, and obesity has led to important changes in liver disease epidemiology that have exacerbated health disparities. Health disparities occur when plausibly avoidable health differences are experienced by socially disadvantaged populations.
Ani Kardashian, Marina Serper, Norah Terrault, Lauren D. Nephew   +3 more
wiley   +1 more source

In Silico to In Cerebro—Development of the Orexin Receptor Antagonist “Photorexant” for Photomodulation In Vitro and in Mouse Brains

Angewandte Chemie International Edition, EarlyView.
Following a structure‐based design approach, photoswitchable derivatives of the FDA‐approved drug suvorexant were designed, docked, synthesized, and characterized pharmacologically at the orexin 1 and 2 receptors (OX1R and OX2R). Optimized “photorexant” showed up to an 11‐fold difference in IC50 between photoisomers, enabled dynamic and reversible ...
Marcus Angermann, Marie H. Deventer, Vicente Ledesma‐Martin, Nuno Martinho, Alix Flake, Silvia Mori, Angel Nuñez, Jaime Pignatelli, Rita C. Guedes, Christophe P. Stove, Michael Decker   +10 more
wiley   +1 more source

Em prol da ciência, em benefício da saúde On behalf of science and for the benefit of health

Estudos de Sociologia, 2007
Este trabalho discute a trajetória da Sociedade de Medicina e Cirurgia de São Paulo no período que se estende entre 1895 e 1920, voltando-se para a análise de seus objetos de estudos, organização institucional e principais iniciativas.
Luiz Antonio Teixeira
doaj  

Morphological variation in atlas and axis of Neotropical spiny rats (Rodentia, Echimyidae)

The Anatomical Record, EarlyView.
Abstract The unique morphologies of the first two cervical vertebrae, the atlas and axis, represent a significant innovation in mammalian evolution. These structures support the weight of the head and enable intricate movements of the head and neck.
Thomas Furtado da Silva Netto, João Felipe Leal Kaiuca, Adriana Itatí Olivares, William Corrêa Tavares   +3 more
wiley   +1 more source

Guía de práctica clínica mexicana para el diagnóstico y tratamiento de las dislipidemias y enfermedad cardiovascular aterosclerótica. [PDF]

Arch Cardiol Mex, 2022
Pavía-López AA, Alcocer-Gamba MA, Ruiz-Gastelum ED, Mayorga-Butrón JL, Mehta R, Díaz-Aragón FA, Aldrete-Velasco JA, López-Juárez N, Cruz-Bautista I, Chávez-Mendoza A, Secchi-Nicolás NC, Guerrero-Martínez FJ, Cossio-Aranda JE, Mendoza-Zubieta V, Fanghänel-Salmon G, Valdivia-Proa M, Olmos-Domínguez L, Aguilar-Salinas CA, Dávila-Maldonado L, Vázquez-Rangel A, Pavia-Aubry V, Nava-Hernández MLA, Hinojosa-Becerril CA, Anda-Garay JC, Ríos-Ibarra MOL, Berni-Betancourt AC, López-Cuellar J, Araiza-Garaygordobil D, Rivera-Reyes R, Borrayo-Sánchez G, Tapia-Hernández M, Cano-Nigenda CV, Guerra-López A, Elías-López J, Figueroa-Morales MA, Montaño-Velázquez BB, Velasco-Hidalgo L, Rodríguez-Lozano AL, Pimentel-Hernández C, Baquero-Hoyos MM, Romero-Moreno F, Rodríguez-Vega M.   +41 more
europepmc   +1 more source

The impact of COVID‐19 pre‐university education on first‐grade medical students. A performance study of students of a Department of Histology

Anatomical Sciences Education, Volume 18, Issue 3, Page 254-263, March 2025.
Abstract The recent coronavirus disease (COVID‐19) forced pre‐university professionals to modify the educational system. This work aimed to determine the effects of pandemic situation on students' access to medical studies by comparing the performance of medical students.
José Manuel García, David Sánchez‐Porras, Miguel Etayo‐Escanilla, Paula Ávila‐Fernández, Olimpia Ortiz‐Arrabal, Miguel‐Ángel Martín‐Piedra, Fernando Campos, Óscar‐Darío García‐García, Jesús Chato‐Astrain, Miguel Alaminos   +9 more
wiley   +1 more source

Development of interactive MRI‐based 3D visualization tools for neuroanatomy education in Latin America

Anatomical Sciences Education, EarlyView.
Abstract The study of neuroanatomy is fundamental in many scientific fields. Despite this, it is a challenging subject for students. As technology evolves, it is being increasingly incorporated into educational methods, including the teaching of neuroanatomy. Three‐dimensional (3D) visualizations are well suited for displaying neuroanatomy.
Merlin J. Fair, Diego Cureño, Alejandro De León Cuevas, Paola Ocampo Luna, Marta Bianciardi, María G. García‐Gomar   +5 more
wiley   +1 more source

Traditional knowledge for promotion of socioeconomic inclusion of local communities

Revista de Saúde Pública
This paper discusses the key role played by public research institutes for promoting socioeconomic inclusion of local communities based on traditional knowledge and traditional medicine.
Waldemiro Francisco Sorte Junior
doaj  

One‐Pot Synthesis of a Small Synthetic Ligand for Antibody Purification

Biotechnology and Bioengineering, EarlyView.
One‐pot liquid‐phase synthesis of the synthetic ligand B1Al2A2 enables controllable ligand density and efficient capture of IgG and IgY with high recovery and purity, streamlining small‐ligand affinity purification workflows. ABSTRACT The development of synthetic affinity ligands offers a cost‐effective alternative to traditional biological ligands ...
Carolina Mota Natal, Catarina Domingos, André Nascimento, José Mendes, Afonso B. Ruiz, Ana Margarida Gonçalves Carvalho Dias, Luisa M. Ferreira, Cristina Peixoto, Ana Cecília Afonso Roque   +8 more
wiley   +1 more source