Results 31 to 40 of about 3,954 (210)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

The application of the social model of disability and Wilson’s model of information behaviour towards effective service delivery for students with disabilities within an academic library context

Inkanyiso, 2019
This paper explores the applicability of the social model of disability and Wilson’s model of information seeking behaviour for effective service delivery to students with disabilities in the context of academic libraries.
Dorothy Eneya, B. J. Mostert
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Power and Status (and Lack Thereof) in Academe: Academic Freedom and Academic Librarians

In the Library with the Lead Pipe, 2020
Academic librarians (AL) do not experience full academic freedom (AF) protections, and AF for AL is not well studied. We surveyed ALs, with over 600 responses. This article focuses on librarian faculty status and how it intersects with AF perceptions and
Danya Leebaw, Alexis Logsdon
doaj  

Essential and core books for veterinary medicine

Journal of the Medical Library Association, 2018
Objectives:This study defined core and essential lists of recent, English-language veterinary medicine books using a data-driven methodology for potential use by a broad audience, including libraries that are building collections supporting veterinary ...
Heather K. Moberly, Jessica R. Page
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Academic Libraries

Technical Services Quarterly, 2007
As strategic plans developed in the 1990s reach maturity, it is crucial to question the use and impact of strategic planning in academic libraries. This article reviews the origins of strategic planning and its various uses in academic libraries, and then discusses several positive and negative impacts of strategic planning on academic libraries and ...
Brown, Walter A., Blake Gonzalez, Barbara   +1 more
openaire   +2 more sources

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Digital humanities in US academic libraries: case studies [PDF]

Digital Transformation and Society
Purpose – Digital Humanities is a robust area of research and practice at universities and their libraries across the world. This case study investigates the unique DH practices of seven US academic libraries to provide insights into how varied academic ...
Kelda Habing, Lian Ruan
doaj   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source