Results 41 to 50 of about 17,473,500 (289)
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye +33 more
wiley +1 more source
Hegel and the Sciences of Spirit (Geisteswissenschaften) [PDF]
, 2023 Brolly. Journal of Social Sciences | ISSN (print) 2516-869X; ISSN (online) 2516-8703 | eSupplement - November 2023 - Brolly+ | Hegel and the Sciences of Spirit (Geisteswissenschaften) | *This eSupplement reproduces: Hegel and the Sciences of Spirit ...
Onu, Mădălin
core +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Books for an Open Society - Experts' View
Knygotyra, 2003 Evaluation of the academic literature publishing in Lithuania was twofold. Some of the experts estimated situation as critical, others stressed the obvious improvement in the field of academic publishing.
Arūnas Poviliūnas
doaj +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Predators and hijackers in academic publishing
European Journal of General Practice, 2015 A theme that has recently received increasing attention in medical publishing is predatory journals.
Igor, Švab, Irena, Makivić
openaire +2 more sources
Publishing 101: The Basics of Academic Publishing [PDF]
The Serials Librarian, 2008 ABSTRACT Rolnik's preconference went well beyond the “business of publishing from a very basic perspective” as described in the conference program. Rolnik's preconference described the publishing market, operations within publishing companies, and how publishers find content. Dr.
Zachary Rolnik +2 more
openaire +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source