Results 41 to 50 of about 522,074 (256)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

The Scandal of Academic Publishing

open access: yesPublishing Research Quarterly
Abstract Much is rotten in academic publishing, but it is easier to hold noses than do anything more fundamental about the stench. The five companies dominating the industry have grown fat on the backs of free academic labour. Why do academics (and so their research funders, their employers and the taxpayer) continue to subsidise the ...
openaire   +2 more sources

Publishing 101: The Basics of Academic Publishing [PDF]

open access: yesThe Serials Librarian, 2008
ABSTRACT Rolnik's preconference went well beyond the “business of publishing from a very basic perspective” as described in the conference program. Rolnik's preconference described the publishing market, operations within publishing companies, and how publishers find content. Dr.
Zachary Rolnik   +2 more
openaire   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Predicting scientific research output at the University of KwaZulu-Natal

open access: yesSouth African Journal of Science, 2017
Academic members of staff at the University of KwaZulu-Natal (UKZN) are expected to publish in research journals that have been accredited by the South African based Department of Higher Education and Training.
Mike Murray
doaj   +1 more source

Predators and hijackers in academic publishing

open access: yesEuropean Journal of General Practice, 2015
A theme that has recently received increasing attention in medical publishing is predatory journals.
Igor, Švab, Irena, Makivić
openaire   +2 more sources

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Thank you to Laparoscopic, Endoscopic and Robotic Surgery peer reviewers

open access: yesLaparoscopic, Endoscopic and Robotic Surgery, 2022
Qingjje Zeng, Jin Wang
doaj   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

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