Results 51 to 60 of about 17,473,500 (289)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Academic publishing in Nepal

Journal of Karnali Academy of Health Sciences, 2022
Globally academic publishing is a high profit industry. Most of the work associated with manuscripts is carried out by academics for free. The article examines the academic publishing industry in Nepal.
Pathiyil Ravi Shankar, Bhuvan KC, Kapil Amgain   +2 more
doaj  

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Evaluation Method for Highly Cited Scholars based on CNKI data

Zhishi guanli luntan
[Purpose/Significance] This study aims to measure the influence of scholars objectively and scientifically, identify a group of scholars with rich scientific research achievements and outstanding academic influence in China in the past 10 years, and ...
Wu Junhong, Zheng Xinyu, Sun Jun, Xiao Hong, Tang Liyun
doaj   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Open government partnership as a platform for advancing open education policy

Open Praxis, 2015
An exciting new avenue for establishing and expanding national commitments to open education has emerged through the Open Government Partnership (OGP), a multilateral initiative that aims to secure commitments from governments to make their governance ...
Jan Gondol, Nicole Allen
doaj   +3 more sources

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

The Enclosure and Alienation of Academic Publishing: Lessons for the Professoriate

tripleC: Communication, Capitalism & Critique, 2012
This paper interrogates and situates theoretically from a Marxist perspective various aspects and tensions that inhere in the contemporary academic publishing environment. The focus of the article is on journal publishing.
Wilhelm Peekhaus
doaj   +1 more source

The Scandal of Academic Publishing

Publishing Research Quarterly
Abstract Much is rotten in academic publishing, but it is easier to hold noses than do anything more fundamental about the stench. The five companies dominating the industry have grown fat on the backs of free academic labour. Why do academics (and so their research funders, their employers and the taxpayer) continue to subsidise the ...
openaire   +2 more sources

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source