Results 61 to 70 of about 613,085 (262)

How do grit and academic stress influence academic performance? The role of academic self-efficacy as a mediator and moderator variable

Psikohumaniora: Jurnal Penelitian Psikologi
Online learning systems are currently the primary approach to delivering information and facilitating learning for postgraduate students, replacing traditional in-person methods in many contexts. To succeed academically in this environment, students must
Muh Daud, Dian Novita Siswanti, Dwi Yan Nugraha, Edwin Adrianta Surijah   +3 more
doaj   +1 more source

Secretory Ig a in Saliva and Academic Stress

International Journal of Immunopathology and Pharmacology, 2004
Several reports have proposed that the concentration of secretory immunoglobulin A (S-IgA) in saliva is an indicator of psychological stress. With this in mind, we decided to examine it in 10 second year medical student volunteers at Kawasaki Medical School course between May 4 and July 13, 2000 and discussed the relationship between S-IgA and the ...
T, Otsuki, H, Sakaguchi, T, Hatayama, A, Takata, F, Hyodoh, S, Tsujita, A, Ueki, K, Morimoto   +7 more
openaire   +2 more sources

Anxiety, rumination and academic stress

International journal of health sciences, 2022
Background: The pandemic, caused by this new virus, has had an impact on various areas of health such as psychological well-being, since it generated fear of contagion of this disease, in addition to not having the necessary resources to face this new reality imposed by the covid-19; This caused another challenge to face in this pandemic.
Palacios Garay, Jessica Paola, Alarcón Díaz, Mitchell Alberto, Venegas Mejía, Clotilde Paula, Loayza López, María Antonieta   +3 more
openaire   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Academic stress, perceived parental pressure, and anxiety related to competitive entrance examinations and the general well-being among adolescents – A cross-sectional survey from Karnataka, India

Journal of Education and Health Promotion
BACKGROUND: In this competitive world, students undergo various scholastic stress and mental health issues. The scholastic stress has a great impact on students’ life and results in the prevalence of several psychological consequences such as stress ...
Khriebeizonuo Pienyu, Binu Margaret, Anjalin D’Souza   +2 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Perfectionism, Coping, and Underachievement in Gifted Adolescents: Avoidance vs. Approach Orientations

Education Sciences, 2016
Perfectionism can influence how one approaches challenges and deals with setbacks, and, consequently, can inhibit or facilitate achievement. The present study (1) explored the relationship between Frost’s six dimensions of perfectionism and five types of
Emily Mofield, Megan Parker Peters, Sumita Chakraborti-Ghosh   +2 more
doaj   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source