Results 261 to 270 of about 6,234,325 (397)

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source

Invisible disabilities and college academic success: New evidence from a mediation analysis. [PDF]

Soc Sci Res
Myers A, Halpern-Manners A, McLeod JD.
europepmc   +1 more source

Beyond Traditional RAFT Polymerization: Emerging Strategies and Future Perspectives; A Third Update

Advanced Science, EarlyView.
This review explores recent advances in the past five years for non‐traditional RAFT polymerization, focusing on new activation strategies, sustainable depolymerization, and integration with automated and AI‐driven synthesis. Together, these innovations advance polymer chemistry and reveal how the pieces of the non‐traditional RAFT puzzle are steadily ...
Vianna F. Jafari, James L. Grace, Jiajia Li, Joji Tanaka, Glen R. Jones, Athina Anastasaki, Wei You, Jian Zhu, Masami Kamigaito, Cyrille Boyer, Greg G. Qiao   +10 more
wiley   +1 more source

Is medical school culture conducive to women's academic success? a survey on faculty perceptions and experiences of gender equity. [PDF]

BMC Med Educ
Shorey S, Gan YH, Cavert MS, Archuleta S.   +3 more
europepmc   +1 more source

Giant Isotope Effect in Metal–Organic Frameworks Boosts Unprecedented Photo‐ and Radio‐Luminescence Enhancement

Advanced Science, EarlyView.
Deuterated MOFs in this work exhibited unprecedented giant luminescence isotope effect via O─H oscillator suppression, achieving maximal solid‐state materials emission enhancement. This yields significantly improved X‐ray detection sensitivity and imaging resolution, marking the first integration of MOFs with isotopic luminescence and opening new ...
Junhao Lu, Dan Zhou, Xianhuan Hao, Hao Lu, Zhongyuan Zhang, Yuhuan Jia, Sen Mei, Ye Huang, Songbai Tang, Zhiyong Peng, Lanhua Chen, Mengjia Yuan, Lixi Chen, Shuaihua Wang, Meiling Feng, Yanlong Wang, Shuao Wang   +16 more
wiley   +1 more source

Factors associated with infectious diseases fellowship academic success. [PDF]

Med Educ Online
Khodadadi RB, Yetmar ZA, Domonoske CL, Razonable RR.   +3 more
europepmc   +1 more source

TRIM40 Drives Pathological Cardiac Hypertrophy and Heart Failure via Ubiquitination of PKN2

Advanced Science, EarlyView.
This study identifies the E3 ligase TRIM40 as a key driver of pathological cardiac hypertrophy. TRIM40 binds PKN2 via its B‐box domain and, through its C29‐dependent catalytic activity, mediates K63‐linked ubiquitination of PKN2. This modification enhances PKN2 phosphorylation at Ser815, thereby driving hypertrophy.
Risheng Zhao, Xiaoli Cui, Huizhu Du, Zhuoqun Wang, Chang Liu, Linxin Zhang, Jianing Qi, Di Yang, Hui Yu, Shuang Yan, Wei Liu, Haiming Sun, Mengyang Wang   +12 more
wiley   +1 more source

Estimating Students' Academic Success in the Preclinical Stage of Undergraduate Medical Education Using the Admission Test Approach. [PDF]

J Adv Med Educ Prof
Diarsvitri W, Garianto E, Indrawati R, Sulistiani W.   +3 more
europepmc   +1 more source

A Case Study of the Academic Success of Somali Refugee Students in a Two-Year Community College.

, 2015
Mustafa M. Ibrahim
openalex   +1 more source

The academic chair: Achieving success in a rapidly evolving health-care environment [PDF]

, 2018
Gelberman, Richard H, Herndon, James H, Salazar, Dane H, Vail, Thomas P, Zuckerman, Joseph D   +4 more
core   +1 more source