Results 81 to 90 of about 1,565,968 (306)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

IMPROVING SCHOOL PRINCIPAL COMPETENCE IN IMPLEMENTING ACADEMIC SUPERVISION THROUGH MONITORING AND EVALUATION METHODS IN INDRAGIRI HULU REGENCY

Jurnal PAJAR (Pendidikan dan Pengajaran), 2020
This research is motivated by the large number of principals who do not conduct supervision and evaluation on academic supervision in schools, because they just serve as principals, resulting in low learning quality.
Sartana
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Implementasi Supervisi Akademik Berbasis Coaching oleh Kepala Sekolah dalam Meningkatkan Kompetensi Pedagogik Guru Sekolah Dasar Negeri Cicalengka 06 Kabupaten Bandung

Edukasia
This research is based on teachers' teaching abilities and pedagogical abilities which are still low. This research aims to obtain an overview of the implementation of coaching-based academic supervision in improving teacher pedagogical competence ...
Suharyanto H. Soro, Arif Rahman Hakim, Sri Rahayu, Witi Restuning Pangestuti   +3 more
doaj   +1 more source

Intuitive expertise in ICT graduate supervision [PDF]

, 2002
Intuitive expertise in the application of advanced interdisciplinary facilitation is the subject of this personal reflection on the graduate supervisory style of Professor David Squires in computers in education.
Jameson, Jill
core   +2 more sources

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

A peer-driven community-based supervisory model: development from an evaluation of an ethics workshop for doctoral students undertaking research with children [PDF]

, 2014
Differing doctoral supervision models currently exist. Three key conceptual supervisory models relevant to doctoral students from within the healthcare professions were identified from a literature review: the ‘functional pre-modern’ model, the ‘team ...
Hunt, Jane, Swallow, Veronica
core  

Enhancing postgraduate supervision through a process of conversational inquiry [PDF]

, 2011
This paper outlines and begins to evaluate a process to build a critical and reflective community of postgraduate supervisors who can develop their supervision practice through reflective conversations, with the sharing of best practice and reference to ...
Bruce Ferguson, Pip, Byrnes, Giselle, Spiller, Dorothy   +2 more
core   +2 more sources

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Pengaruh Academic Supervision Of School Heads Dan Interpersonal Communication Terhadap Teacher Performance Sekolah Dasar Negeri Jakarta Selatan

Tadbir: Jurnal Studi Manajemen Pendidikan, 2020
The purpose of this study is to determine whether there is a direct positive effect from Principal’s academic supervision and interpersonal communication on teacher's performance.
Ratih Kusuma Wardani, Heru Santosa, Desi Rahmawati   +2 more
doaj   +1 more source