Results 41 to 50 of about 10,774 (305)

Brasil: Acima de Tudo!! The Brazilian Armed Forces: Remodeling for a New Era

open access: yesDiálogos, 2017
The history of the Brazilian military has been marked by repeated “reforms” and up-dating efforts to keep abreast of developments abroad.Since World War II such efforts were often weakened, delayed, and reduced by involvement in politics, lack of ...
Frank D McCann
doaj   +3 more sources

Partnerships for Enhanced Engagement in Research (PEER) health: a new programme to facilitate LMIC research capacity

open access: yesThe Lancet Global Health, 2014
Background: The Partnership for Enhanced Engagement in Research (PEER) Health programme, funded by the United States Agency for International Development (USAID), is a new research partnership programme that directly supports researchers from developing ...
Dr. Callie Raulfs-Wang, PhD   +9 more
doaj   +1 more source

Turkey’s Caucasus Policies, 2000-2022

open access: yes, 2023
The emergence of newly independent states in the Caucasus at the end of the Cold War presented challenges to Turkey while enlarging its role. The collapse of the Soviet Union removed the century-old Sovi-et/Russian threat, simultaneously creating a power
Aydın, Mustafa, Aydın,M.
core   +1 more source

α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates

open access: yesFEBS Letters, EarlyView.
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino   +2 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Enhancing learning in the IS academies

open access: yes, 2013
This research brief describes current mechanisms for learning in so-called ‘IS Academies’, collaborative projects of the Dutch Ministry of Foreign Affairs (MFA), academic institutes, and development agencies.
Hilhorst, Thea; id_orcid, van Delft, P
core   +1 more source

CONSIDERATIONS REGARDIND THE SCIENTIFIC GROUNDS FOR SETTING UP SECURITY STRATEGIES [PDF]

open access: yesAnnals: Series on Military Sciences, 2016
The main objective of the paper is to present a point of view on scientific approaches towards the security strategy so as to create opportunities to intensify the exchange of scientific ideas between scientists.
Mihai ILIESCU, Eugen SITEANU
doaj  

Mathematical Instruments Used in the Military Engineering Academies of the Ottomans

open access: yes, 2018
6th IFToMM International Symposium on the History of Machines and Mechanisms (HMM) -- SEP 26-28, 2018 -- Chinese Acad Sci, Inst Hist Nat Sci, Beijing, PEOPLES R CHINAAt the end of 17th century and during 18th century, in order to train elite cadets who ...
Irem Aslan Seyhan, Seyhan, Irem Asian
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

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