Results 61 to 70 of about 10,313 (263)
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Definindo prioridades de gestão de ciência e tecnologia em saúde
Revista de Saúde PúblicaINTRODUÇÃO: A necessidade de gestão da produção científica e tecnológica em saúde está bem estabelecida no Brasil desde a realização da I Conferência Nacional de Ciência e Tecnologia (C&T) em Saúde, em 1994.
Júlio Cesar Rodrigues Pereira +2 more
doaj
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Geoadria, 2007 Besides the central Department of Geography and the Institutes of the University of Zagreb's Faculty of Science, the tradition of development of modern geographic thought and science in Croatia is also associated with other higher-education institutions ...
Damir Magaš
doaj
Stolen Ukrainian universities: An invisible russian weapon [PDF]
Problems and Perspectives in ManagementThis paper explores the issue of “stolen” Ukrainian universities. Over 1,500 Ukrainian educational and research organizations have been seized by Russia, including 289 higher education institutions such as universities, institutes, academies, colleges ...
Alex Plastun, Serhiy Kozmenko
doaj +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
INTEGRATED DIDACTIC DESIGN MODEL FOR ENGINEER OFFICERS' TRAINING: INSIGHTS FROM INTERNATIONAL EXPERIENCE [PDF]
Journal of Defense Resources ManagementThe training of military engineering personnel is mainly carried out on the basis of military institutes, universities and academies. In addition to the specialty, military higher education institutions are aimed at instilling and developing strategic ...
Amil DADASHOV
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On a national academy of science and technological institutions [PDF]
Journal of the Franklin Instituten ...
openaire +1 more source