Results 61 to 70 of about 128,304 (345)

The Current Understanding of Gestational Weight Gain Among Women with Obesity and the Need for Future Research.

NAM Perspectives, 2020
In June 2018, the Roundtable on Obesity Solutions of the National Academies of Sciences, Engineering, and Medicine (the National Academies) held a webinar titled “The Current Understanding of Pre-Pregnancy Weight, Gestational Weight Gain, and the Impacts
A. Siega-Riz, L. Bodnar, N. Stotland, J. Stang   +3 more
semanticscholar   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Emerging Areas of Science: Recommendations for Nursing Science Education from the Council for the Advancement of Nursing Science Idea Festival [PDF]

, 2015
The Council for the Advancement of Nursing Science aims to “facilitate and recognize life-long nursing science career development” as an important part of its mission.
Alt-White, Anna C., Conley, Yvette P., Heitkemper, Margaret M., Henly, Susan J., McCarthy, Ann Marie, McCarthy, Donna O., Moore, Shirley M., Redeker, Nancy S., Stone, Patricia W., Titler, Marita, Wyman, Jean F.   +10 more
core   +1 more source

A Roadmap for Foundational Research on Artificial Intelligence in Medical Imaging: From the 2018 NIH/RSNA/ACR/The Academy Workshop.

Radiology, 2019
Imaging research laboratories are rapidly creating machine learning systems that achieve expert human performance using open-source methods and tools.
C. Langlotz, B. Allen, B. Erickson, Jayashree Kalpathy-Cramer, K. Bigelow, T. Cook, A. Flanders, M. Lungren, David S. Mendelson, J. Rudie, Ge Wang, K. Kandarpa   +11 more
semanticscholar   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Are SREB States Making Progress? Tapping, Preparing and Licensing School Leaders Who Can Influence Student Achievement [PDF]

, 2002
Looks at the progress SREB states are making in developing systems to identify, prepare, and assess future school ...
Andrea Jacobson, Betty Fry, David Hill, Gene Bottoms, Kathy O'Neill   +4 more
core  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Real-Time Systems: Reflections on higher education in the Czech Republic, Hungary, Poland and Slovenia [PDF]

, 2003
Real-time systems (An ICT definition)\ud In real-time multiprocessing there is the extra requirement that the system complete its response to any input within a certain critical time.
File, Jon, Goedegebuure, Leo
core   +1 more source