Results 71 to 80 of about 128,304 (345)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Exploring African American community perspectives about genomic medicine research: A literature review

SAGE Open Medicine, 2020
Genomic medicine research is an important topic in the African American health care community. African American nurses and advance practice nursing professionals are poised to encourage and educate themselves and their communities about the importance of
Rachele M Hendricks-Sturrup, Lauren M Edgar, Tracey Johnson-Glover, Christine Y Lu   +3 more
doaj   +1 more source

Audiovisual research collections and their preservation [PDF]

, 2008
The basic problem of primary audio and video research materials is clearly shown by the survey: A great and important part of the entire heritage is still outside archival custody in the narrower sense, scattered over many institutions in fairy small ...
Schüller, Dietrich
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Point of care affirmability of patient safety criteria at tertiary healthcare level in Peshawar-Pakistan: a cross-sectional evaluation

Khyber Medical University Journal
Objective: To evaluate the level of compliance with the World Health Organization’s (WHO) recommended patient safety criteria in tertiary healthcare facilities in Peshawar-Pakistan.
Basharat Hussain, Sheraz Fazid, Ihtesham Ul Haq, Zia Ul-Haq   +3 more
doaj   +1 more source

Virtual Academies for companies and educational institutions

Information Services & Use, 1999
This session is adressed to companies and educational content providers who are looking for a pragmatic tele-learning approach. We will demonstrate tele-learning as a practical proven method for job oriented training at low costs – especially for big companies.
openaire   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Health Literacy: An overview of an emerging field [PDF]

, 2011
According to the National Adult Literacy Survey, nearly 90 million American adults test below a high school level for literacy skills (Kirsch, Jungeblut, Jenkins & Kolstad, 1993).Because most health materials are written at least at the high school level,
Flaherty, Mary Grace
core   +1 more source

Long-term research challenges in wind energy – a research agenda by the European Academy of Wind Energy

, 2016
. The European Academy of Wind Energy (eawe), representing universities and institutes with a significant wind energy programme in 14 countries, has discussed the long-term research challenges in wind energy.
G. Kuik, J. Peinke, R. Nijssen, D. Lekou, J. Mann, Jens Nørkær Sørensen, C. Ferreira, J. V. Wingerden, D. Schlipf, P. Gebraad, H. Polinder, A. Abrahamsen, G. Bussel, J. Sørensen, P. Tavner, C. Bottasso, M. Muskulus, D. Matha, H. Lindeboom, S. Degraer, Oliver Kramer, S. Lehnhoff, M. Sonnenschein, P. Sørensen, R. Künneke, P. Morthorst, K. Skytte   +26 more
semanticscholar   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source