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Survey of Ophthalmology, 1998
Acanthamoeba species are an important cause of microbial keratitis that may cause severe ocular inflammation and visual loss. The first cases were recognized in 1973, but the disease remained very rare until the 1980s, when an increase in incidence mainly associated with contact lens wear was reported.
C D, Illingworth, S D, Cook
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Acanthamoeba species are an important cause of microbial keratitis that may cause severe ocular inflammation and visual loss. The first cases were recognized in 1973, but the disease remained very rare until the 1980s, when an increase in incidence mainly associated with contact lens wear was reported.
C D, Illingworth, S D, Cook
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Classification of Acanthamoeba
Clinical Infectious Diseases, 1991Members of the genus Acanthamoeba are being isolated with increasing frequency from clinical specimens, especially contact lens solutions. Although the genus was first established in 1931, considerable confusion about its taxonomic classification existed in the literature until recently.
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Clinical Infectious Diseases, 1991
Human serum contains antibodies, mainly of the IgM and IgG isotypes, to pathogenic species of Acanthamoeba. This, as well as the capacity of these amebas to activate complement via the alternative pathway, may be a first-line defense against acanthamoeba infections in humans.
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Human serum contains antibodies, mainly of the IgM and IgG isotypes, to pathogenic species of Acanthamoeba. This, as well as the capacity of these amebas to activate complement via the alternative pathway, may be a first-line defense against acanthamoeba infections in humans.
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Clinical Infectious Diseases, 1991
Acanthamoeba is a free-living ameba that is present in all types of environments throughout the world. The recent increase in cases of keratitis, especially in relation to an increase in the use of contact lenses, is probably due to the omnipresence of the organism as a result of the pronounced resistance of its cysts to disinfection and desiccation ...
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Acanthamoeba is a free-living ameba that is present in all types of environments throughout the world. The recent increase in cases of keratitis, especially in relation to an increase in the use of contact lenses, is probably due to the omnipresence of the organism as a result of the pronounced resistance of its cysts to disinfection and desiccation ...
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Reviews in Medical Microbiology, 1994
Acanthamoeba is a small, free-living amoeba which is characterized by a feeding and replicating trophozoite and dormant cyst stage. The resistance of acanthamoeba cysts to extremes of temperature, disinfection and desiccation accounts for the ubiquitous distribution of the organism in our ...
S. Kilvington, D. G. White
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Acanthamoeba is a small, free-living amoeba which is characterized by a feeding and replicating trophozoite and dormant cyst stage. The resistance of acanthamoeba cysts to extremes of temperature, disinfection and desiccation accounts for the ubiquitous distribution of the organism in our ...
S. Kilvington, D. G. White
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Ophthalmologica, 2010
The first Acanthamoeba keratitis was found in 1974, and the first Japanese case was reported in 1988. We devided the clinical features to three stages, and described clinical features in each stage. Diagnosis was suspected from clinical history and features, and definite diagnosis was made by direct examination or culture.
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The first Acanthamoeba keratitis was found in 1974, and the first Japanese case was reported in 1988. We devided the clinical features to three stages, and described clinical features in each stage. Diagnosis was suspected from clinical history and features, and definite diagnosis was made by direct examination or culture.
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Role of Tear Anti-Acanthamoeba IgA in Acanthamoeba Keratitis
Cornea, 2000Acanthamoeba keratitis is a sight-threatening corneal disease caused by pathogenic free-living amoebae.1The organisms have been isolated from a wide variety of environments and from nasopharyngeal washes of asymptomatic individuals. 1Contact lens wear, practiced by over 25 million individuals in the United States, is the leading risk factor.
J Y, Niederkorn +9 more
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The Pediatric Infectious Disease Journal, 1986
Acanthamoeba infection of the cornea is an entity now recognized with increasing frequency. We saw two cases of Acanthamoeba sclerokeratitis in contact lens wearers in whom scleritis (anterior and posterior) played a central role in the clinical course of the disease.
M J, Mannis +4 more
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Acanthamoeba infection of the cornea is an entity now recognized with increasing frequency. We saw two cases of Acanthamoeba sclerokeratitis in contact lens wearers in whom scleritis (anterior and posterior) played a central role in the clinical course of the disease.
M J, Mannis +4 more
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The immunobiology of Acanthamoeba keratitis
Microbes and Infection, 2006Acanthamoeba spp. are free-living amoebae that cause Acanthamoeba keratitis, a blinding corneal infection. The innate immune apparatus is crucial for the resolution of the disease. With the exception of mucosal antibody, elements of the adaptive immune system fail to prevent infection or contribute to its resolution in experimental animals.
Daniel W, Clarke, Jerry Y, Niederkorn
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The pathophysiology of Acanthamoeba keratitis
Trends in Parasitology, 2006Acanthamoeba keratitis is a sight-threatening infection of the ocular surface that is produced by several free-living amebae of the genus Acanthamoeba. Infection is usually initiated by Acanthamoeba-contaminated contact lenses and produces exquisite pain and ulceration of the ocular surface.
Daniel W, Clarke, Jerry Y, Niederkorn
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