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Challenges in Acanthamoeba Keratitis: A Review [PDF]

Journal of Clinical Medicine, 2021
To review challenges in the diagnosis and management of Acanthamoeba keratitis (AK), along with prognostic factors, in order to help ophthalmologists avoid misdiagnosis, protracted treatment periods, and long-term negative sequelae, with an overarching goal of improving patient outcomes and quality of life, we examined AK studies published between ...
Giuseppe Varacalli, Thomas Dohlman, Antonio Di Zazzo   +2 more
exaly   +3 more sources

The pathogenesis, risk factors, diagnosis and treatment of Acanthamoeba keratitis [PDF]

Frontiers in Medicine
Acanthamoeba keratitis (AK) is a rare corneal disease that can lead to permanent visual impairment. Its incidence is relatively low when compared with that of other forms of infectious keratitis.
Mingliang Bao, Hai Bao, Shuqing Wang, Hongyan Zhou   +3 more
doaj   +2 more sources

Genetic diversity of Acanthamoeba and clinical outcome predictors in Danish patients with Acanthamoeba keratitis. [PDF]

Acta Ophthalmol
Abstract Purpose Acanthamoeba keratitis (AK) is a severe corneal infection with potential detrimental effects on visual outcome and quality of life, primarily affecting young contact lens wearers. We report Acanthamoeba genotypes, subtypes and clinical outcome from Danish patients with AK. Methods Thirty‐nine PCR‐positive AK cases diagnosed and treated
Skovdal SM, Stensvold CR, Nielsen HV, Nielsen SE, Hjortdal J, Ivarsen A.   +5 more
europepmc   +2 more sources

Acanthamoeba keratitis - A review. [PDF]

Indian J Ophthalmol
This is a comprehensive review after a thorough literature search in PubMed-indexed journals, incorporating current information on the pathophysiology, clinical features, diagnosis, medical and surgical therapy, as well as outcomes of Acanthamoeba keratitis (AK).
Raghavan A, Rammohan R.
europepmc   +4 more sources

Fungal keratitis complicating the diagnosis of Acanthamoeba keratitis [PDF]

Medical Mycology Case Reports
A 42-year-old woman was referred to an emergency department. She had an unresponsive corneal ulcer that was initially diagnosed as Herpes simplex virus keratitis. Later, the microbiological studies revealed fungal keratitis.
Mehrnaz Atighehchian, Alireza Latifi, Zohreh Nozarian, Fahimeh Asadi Amoli, Mehran Zarei-Ghanavati   +4 more
doaj   +2 more sources

Acanthamoeba keratitis [PDF]

BMJ, 1988
Clotrimazole is an antifungal agent that has been shown to have excellent in vitro activity against most strains of Acanthamoeba. We encountered four patients who developed Acanthamoeba keratitis while wearing contact lenses that had been stored in homemade saline. Their medical treatment regimens included the use of topical 1% clotrimazole.
D C Warhurst, P G Mann
  +12 more sources

Outcomes of amoebic, fungal, and bacterial keratitis: A retrospective cohort study.

PLoS ONE, 2022
BackgroundAcanthamoeba keratitis is challenging to treat and thought to result in poor outcomes, but very few comparative studies exist to assess whether ulcers caused by Acanthamoeba are worse than those caused by bacteria or fungus.MethodsIn a ...
Caitlin A Moe, Prajna Lalitha, N Venkatesh Prajna, Jeena Mascarenhas, Muthiah Srinivasan, Manoranhan Das, Arun Panigrahi, Revathi Rajaraman, Gerami D Seitzman, Catherine E Oldenburg, Thomas M Lietman, Jeremy D Keenan   +11 more
doaj   +2 more sources

Acanthamoeba epitheliopathy: Importance of early diagnosis

American Journal of Ophthalmology Case Reports, 2022
Purpose: To describe two cases of Acanthamoeba keratitis diagnosed and treated at the epithelial stage of disease and to underscore the importance of early diagnosis on prognosis.
Gavin Li, Nakul Shekhawat
doaj   +1 more source

Acanthamoeba keratitis [PDF]

British Journal of Ophthalmology, 1994
We read with interest the report by Radford et al on the incidence of acanthamoeba keratitis and the suggested relation with hardness of water.1 However, we disagree with their findings and believe their study is flawed for two reasons. This paper discusses the flaws.
Seal, D., Beattie, T.K., Tomlinson, A., Fan, D., Wong, E.   +4 more
openaire   +6 more sources

Case series: Delayed diagnoses of Acanthamoeba keratitis

American Journal of Ophthalmology Case Reports, 2020
Purpose: To describe two cases of Acanthamoeba keratitis in contact lens wearers misdiagnosed as Herpes simplex keratitis. Observations: Case 1 is a 54-year-old male that was misdiagnosed with Herpes simplex keratitis who developed advanced Acanthamoeba ...
Moon Jeong Lee, Divya Srikumaran, Sidra Zafar, Mahsa Salehi, Tiffany S. Liu, Fasika A. Woreta   +5 more
doaj   +1 more source