Results 31 to 40 of about 5,202 (207)

Acanthamoeba induces cell-cycle arrest in host cells

, 2004
Acanthamoeba can cause fatal granulomatous amoebic encephalitis (GAE) and eye keratitis. However, the pathogenesis and pathophysiology of these emerging diseases remain unclear.
Alsam, S., Stins, M., Khan, Naveed Ahmed, Sissons, J., Kim, K.S., Jayasekera, S.   +5 more
core   +1 more source

The effect of surface treatment of silicone hydrogel contact lenses on the attachment of Acanthamoeba castellanii trophozoites

, 2009
Aims to determine if plasma surface treatment of Focus Night & Day silicone hydrogel contact lenses affects the attachment of Acanthamoeba. Unworn lotrafilcon A contact lenses with (Focus Night & Day) and with out surface treatment and Acuvue ...
Tomlinson, Alan, Beattie, Tara K.
core   +1 more source

Acanthamoeba genotype T4 from the UK and Iran and isolation of the T2 genotype from clinical isolates

, 2005
The majority of the keratitis-causing Acanthamoeba isolates are genotype T4. In an attempt to determine whether predominance of T4 isolates in Acanthamoeba keratitis is due to greater virulence or greater prevalence of this genotype, Acanthamoeba ...
Warhurst, D., Rezaian, M., Maghsood, A.H., Sissons, James, Khan, Naveed Ahmed, Maghsood, Amir Hossein, Rezaian, Mostafa, Nolder, Debbie, Sissons, J., Warhurst, David, Nolder, D.   +10 more
core   +1 more source

The role of naturally acquired intracellular Pseudomonas aeruginosa in the development of Acanthamoeba keratitis in an animal model.

PLoS Neglected Tropical Diseases
BackgroundAcanthamoeba is an environmental host for various microorganisms. Acanthamoeba is also becoming an increasingly important pathogen as a cause of keratitis.
Binod Rayamajhee, Mark Willcox, Fiona L Henriquez, Ajay Kumar Vijay, Constantinos Petsoglou, Gauri Shankar Shrestha, Hari Kumar Peguda, Nicole Carnt   +7 more
doaj   +1 more source

Acanthamoeba castellanii induces host cell death via a phosphatidylinositol 3-kinase-dependent mechanism

, 2005
Granulomatous amoebic encephalitis due to Acanthamoeba castellanii is a serious human infection with fatal consequences, but it is not clear how the circulating amoebae interact with the blood-brain barrier and transmigrate into the central nervous ...
S. Jayasekera, N. A. Khan, M. Stins, K. S. Kim, Alsam, S., Stins, M., Khan, Naveed Ahmed, Sissons, J., J. Sissons, Kim, K.S., Jayasekera, S., S. Alsam   +11 more
core   +1 more source

Therapeutic Gases in Biomedicine: Updates on Nitric Oxide and Beyond

Advanced Science, Volume 13, Issue 23, 23 April 2026.
Therapeutic gases, including NO, CO, H2S, H2, CO2, O2, and Xe, play vital roles in cellular signaling and repair. This review highlights the emerging carriers and delivery systems that enable controlled, localized gas release for diagnostic and therapeutic applications.
Syed Muntazir Andrabi, Navatha Shree Sharma, Imran Ibn Gani Rather, S. M. Shatil Shahriar, Jingwei Xie   +4 more
wiley   +1 more source

A review of Acanthamoeba keratitis in the middle East and Iran

Journal of Acute Disease, 2019
Acanthamoeba keratitis, a vision-threatening disease, is caused by a free-living amoeba of genus Acanthamoeba. Amoeba is widely distributed all around the world.
Mohammad Hossein Feiz Haddad, Azar Shokri, Habib Habibpour, Seyede Manizhe Heidar Neiadi   +3 more
doaj   +1 more source

Evaluating quality of patient‐reported outcome measures in keratitis: A systematic review

Optometry and Vision Science, Volume 103, Issue 4, April 2026.
ABSTRACT Purpose To evaluate the quality of existing patient‐reported outcome measures (PROMs) used to assess the impact of keratitis on the quality of life (QoL). Methods A literature search was conducted using Embase, PubMed, Scopus, Web of Science, CINAHL, and PsycINFO. The review included PROMs used to assess the impact of keratitis on QoL. Data on
Haile W. Alemu, Sheela E. Kumaran, Nicole Carnt, Aragaw K. Assaye, Pawan Baral, Konrad Pesudovs   +5 more
wiley   +1 more source

Diagnosis of Acanthamoeba keratitis in Mashhad, Northeastern Iran: A Gene-Based PCR Assay

Iranian Journal of Parasitology, 2021
Background: The genus Acanthamoeba is a free-living opportunistic protozoan parasite, which widely distributed in soil and fresh water. Acanthamoeba keratitis, which causes a sight-threating infection of the cornea, is going to rise in Iran and worldwide.
Nazgol KHOSRAVINIA, Abdolmajid FATA, elham MOGHADDAS, Bibi Razieh HOSSEINI FARASH, Mohammad Reza SADAGHAT, Ali Raza ESLAMPOUR, Lida JARAHI   +6 more
doaj  

What We Can Do in Infectious Keratitis, Except for Conventional Antimicrobial‐Based Therapies: Major Narrative Review

Health Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background and Aims Infectious keratitis (IK) is classified as a critical ophthalmic emergency, with the potential to result in vision‐impairing complications. The treatment approach involves the use of pharmacological antimicrobial agents in combination with surgical interventions.
Kasra Cheraqpour
wiley   +1 more source