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Pathogenesis of Acanthamoeba Keratitis [PDF]

The Ocular Surface, 2010
Acanthamoeba keratitis (AK) is a serious infection of the cornea. At present, diagnosis of the disease is not straightforward and treatment is very demanding. While contact lens wear is the leading risk factor for A K, Acanthamoeba parasites are increasingly recognized as an important cause of keratitis in non-contact lens wearers.
openaire   +2 more sources

The biology of Acanthamoeba keratitis

Experimental Eye Research, 2021
Acanthamoeba keratitis (AK) is a rare protozoal infection of the cornea. At least eight species of Acanthamoeba are known to cause this sight-threatening disease of the ocular surface. Acanthamoeba spp. exist in a wide array of niches ranging from thermal springs to under ice and every conceivable habitat in between.
openaire   +3 more sources

Description of Virulent Factors and Horizontal Gene Transfers of Keratitis-Associated Amoeba Acanthamoeba Triangularis by Genome Analysis

Pathogens, 2020
Acanthamoeba triangularis strain SH 621 is a free-living amoeba belonging to Acanthamoeba ribo-genotype T4. This ubiquitous protist is among the free-living amoebas responsible for Acanthamoeba keratitis, a severe infection of human cornea.
Issam Hasni, Julien Andréani, Philippe Colson, Bernard La Scola   +3 more
doaj   +1 more source

The role of naturally acquired intracellular Pseudomonas aeruginosa in the development of Acanthamoeba keratitis in an animal model.

PLoS Neglected Tropical Diseases
BackgroundAcanthamoeba is an environmental host for various microorganisms. Acanthamoeba is also becoming an increasingly important pathogen as a cause of keratitis.
Binod Rayamajhee, Mark Willcox, Fiona L Henriquez, Ajay Kumar Vijay, Constantinos Petsoglou, Gauri Shankar Shrestha, Hari Kumar Peguda, Nicole Carnt   +7 more
doaj   +1 more source

Chlorhexidine 0.02% or polyhexamethylene biguanide 0.02% as the main treatment for Acanthamoeba keratitis

Acta Ophthalmologica, EarlyView.
Abstract Purpose To report medical cure and treatment failure rates of Acanthamoeba keratitis (AK) with respect to type of treatment, disease stage and prognostic factors. Methods Electronic records were reviewed for 45 patients with PCR‐positive AK treated at the Department of Ophthalmology, Aarhus University Hospital, Denmark from 2012 to 2025 ...
Anders Ivarsen, Sandra M. Skovdal, Stine Elkjær Nielsen, Christen Rune Stensvold, Henrik Vedel Nielsen, Jesper Hjortdal   +5 more
wiley   +1 more source

A review of Acanthamoeba keratitis in the middle East and Iran

Journal of Acute Disease, 2019
Acanthamoeba keratitis, a vision-threatening disease, is caused by a free-living amoeba of genus Acanthamoeba. Amoeba is widely distributed all around the world.
Mohammad Hossein Feiz Haddad, Azar Shokri, Habib Habibpour, Seyede Manizhe Heidar Neiadi   +3 more
doaj   +1 more source

Understanding Acanthamoeba Keratitis: An In-Depth Review of a Sight-Threatening Eye Infection. [PDF]

Microorganisms
Petrillo F, Tortori A, Vallino V, Galdiero M, Fea AM, De Sanctis U, Reibaldi M.   +6 more
europepmc   +2 more sources

16S/18S metabarcoding versus culture for aetiological assessment in infectious keratitis: A prospective paired‐sample study

Acta Ophthalmologica, EarlyView.
Abstract Purpose Infectious keratitis (IK) is a vision‐threatening condition with diverse microbial aetiologies, yet conventional culture‐based diagnostics often have limited sensitivity. We investigated whether 16S/18S rRNA amplicon‐based next‐generation sequencing (NGS) can enhance aetiological assessment when used alongside standard microbiological ...
Sandra M. Skovdal, Christen Rune Stensvold, Henrik Vedel Nielsen, Stine Elkjær Nielsen, Jesper Hjortdal, Lise Kristensen, Anders Ivarsen   +6 more
wiley   +1 more source

Diagnosis of Acanthamoeba keratitis in Mashhad, Northeastern Iran: A Gene-Based PCR Assay

Iranian Journal of Parasitology, 2021
Background: The genus Acanthamoeba is a free-living opportunistic protozoan parasite, which widely distributed in soil and fresh water. Acanthamoeba keratitis, which causes a sight-threating infection of the cornea, is going to rise in Iran and worldwide.
Nazgol KHOSRAVINIA, Abdolmajid FATA, elham MOGHADDAS, Bibi Razieh HOSSEINI FARASH, Mohammad Reza SADAGHAT, Ali Raza ESLAMPOUR, Lida JARAHI   +6 more
doaj  

Efficacy of 0.2% povidone‐iodine and 0.1% polyhexamethylene biguanide as preoperative antiseptics in equine ophthalmic procedures

Veterinary Ophthalmology, Volume 28, Issue 2, Page 438-447, March 2025.
Abstract Objective This retrospective study evaluates the efficacy of povidone‐iodine (PI) and polyhexamethylene biguanide (PHMB) as preoperative antiseptics in equine ophthalmic procedures. Animals Studied Horses that underwent routine ophthalmic surgery and procedures.
Anna Farkas, Katharina Thieme, Tanawan Soimala, Charlotte K. Jensen, J. Corinna Eule   +4 more
wiley   +1 more source