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We read with interest the report by Radford et al on the incidence of acanthamoeba keratitis and the suggested relation with hardness of water.1 However, we disagree with their findings and believe their study is flawed for two reasons.
Wong, E. +6 more
core +7 more sources
Updates in Acanthamoeba keratitis
PURPOSE. Acanthamoeba keratitis is a potentially blinding microbial disease that has been increasing in incidence during the past two decades. Prognosis of this serious disease had been dismal, but improvement in diagnosis, a better understanding of the ...
Cavanagh H.D. +3 more
core +3 more sources
Clotrimazole is an antifungal agent that has been shown to have excellent in vitro activity against most strains of Acanthamoeba. We encountered four patients who developed Acanthamoeba keratitis while wearing contact lenses that had been stored in homemade saline. Their medical treatment regimens included the use of topical 1% clotrimazole.
D C Warhurst, P G Mann
+11 more sources
Genetic diversity of Acanthamoeba and clinical outcome predictors in Danish patients with Acanthamoeba keratitis. [PDF]
Abstract Purpose Acanthamoeba keratitis (AK) is a severe corneal infection with potential detrimental effects on visual outcome and quality of life, primarily affecting young contact lens wearers. We report Acanthamoeba genotypes, subtypes and clinical outcome from Danish patients with AK. Methods Thirty‐nine PCR‐positive AK cases diagnosed and treated
Skovdal SM +5 more
europepmc +2 more sources
Acanthamoeba epitheliopathy: Importance of early diagnosis
Purpose: To describe two cases of Acanthamoeba keratitis diagnosed and treated at the epithelial stage of disease and to underscore the importance of early diagnosis on prognosis.
Gavin Li, Nakul Shekhawat
doaj +1 more source
Case series: Delayed diagnoses of Acanthamoeba keratitis
Purpose: To describe two cases of Acanthamoeba keratitis in contact lens wearers misdiagnosed as Herpes simplex keratitis. Observations: Case 1 is a 54-year-old male that was misdiagnosed with Herpes simplex keratitis who developed advanced Acanthamoeba ...
Moon Jeong Lee +5 more
doaj +1 more source
Diagnostic Considerations for Non-Acanthamoeba Amoebic Keratitis and Clinical Outcomes
Cases of amoebic keratitis involving species other than Acanthamoeba are hypothesised to be underdiagnosed and poorly understood. Amoebic keratitis is debilitating and associated with chronic visual impairment.
Siobhan Moran +2 more
doaj +1 more source
Contact lenses contamination by Acanthamoeba spp. in Upper Egypt
Background Acanthamoeba spp. are one of the free-living amoeba that spread worldwide causing keratitis. Owing to the increase in the use of lenses, whether for medical or cosmetic purposes, the incidence of disease increases every year.
Faten A. M. Hassan +4 more
doaj +2 more sources
Acanthamoeba species can cause a keratitis misdiagnosed as herpes keratitis or fungal keratitis. We report an unusual dendrite-like anterior stromal keratitis coinfected with Acanthamoeba and Pseudomonas aeruginosa in an orthokeratology contact lens ...
Chih-Chien Hsu
doaj +1 more source
Purpose: To describe a case of recalcitrant Acanthamoeba Keratitis (AK) complicated by medical non-compliance and medication intolerance that was successfully treated with photoactivated chromophore for infectious keratitis corneal collagen cross-linking
Shelly H. Watson +2 more
doaj +1 more source

