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Acanthamoeba, an environmental phagocyte enhancing survival and transmission of human pathogens.

Trends in Parasitology, 2022
The opportunistic protist Acanthamoeba, which interacts with other microbes such as bacteria, fungi, and viruses, shows significant similarity in cellular and functional aspects to human macrophages.
B. Rayamajhee   +5 more
semanticscholar   +1 more source

Acanthamoeba keratitis: a review of biology, pathophysiology and epidemiology

Ophthalmic & physiological optics, 2020
Acanthamoeba keratitis is an infection caused by a unicellular protozoan of the genus Acanthamoeba that is universally widespread. Until now, most cases were reported in contact lens wearers, although it is also a reality for non‐wearers, mostly ...
Ana Paula Gomes de Lacerda, M. Lira
semanticscholar   +1 more source

Applications of medicinal chemistry for drug discovery against Acanthamoeba infections

Medicinal research reviews (Print), 2021
Acanthamoeba is a genus of free‐living amoebae, pervasively found in the environment. Most of its pathogenic species are the causative agent of sight‐threatening Acanthamoeba keratitis and fatal granulomatous amoebic encephalitis.
Usman Ahmed   +4 more
semanticscholar   +1 more source

Acanthamoeba Sclerokeratitis

American Journal of Ophthalmology, 1994
We treated a healthy soft contact lens wearer who developed Acanthamoeba sclerokeratitis in the left eye. The patient had severe pain and ring-shaped subepithelial infiltrates. The keratitis progressed and scleral nodules developed despite aggressive treatment with topical clotrimazole, dibromopropamidine isethionate, and corticosteroids.
P J, Dougherty   +3 more
openaire   +2 more sources

PCR and culture for diagnosis of Acanthamoeba keratitis

British Journal of Ophthalmology, 2020
Background/Aims Acanthamoeba keratitis (AK) is a rare but sight-threatening infection. Molecular diagnosis of corneal scraping has improved the diagnosis of AK. Different molecular targets and conditions have been used in diagnosis thus far.
H. Yera   +9 more
semanticscholar   +1 more source

Acanthamoeba sclerokeratitis

Graefe's Archive for Clinical and Experimental Ophthalmology, 2008
Acanthamoeba scleritis is an uncommon but severe complication of acanthamoeba keratitis. We report the clinical and histopathologic features of a patient with acanthamoeba sclerokeratitis.Review of the patient's clinical records and histopathologic examination of the globe including light microscopy and transmission electron microscopy.Review of the ...
Katayoon B, Ebrahimi   +3 more
openaire   +2 more sources

Acanthamoeba and its pathogenic role in granulomatous amebic encephalitis.

Experimental parasitology, 2019
Acanthamoeba is a free-living amoeba that is widely distributed in the environment. It is an opportunist protist, which is known to cause rare yet fatal infection of the central nervous system (CNS), granulomatous amebic encephalitis (GAE) in humans. GAE
Sonali K Kalra   +4 more
semanticscholar   +1 more source

Acanthamoeba Keratitis

2008
The incidence of Acanthamoeba keratitis has decreased significantly, and it is no longer a reportable condition in the United States. Corneal abrasion and contact lenses play an important role in the development of Acanthamoeba keratitis. One of the most important features of the disease is severe pain, which is atypical for herpes simplex.
J P, McCulley   +2 more
openaire   +2 more sources

Acanthamoeba Keratitis

Survey of Ophthalmology, 1998
Acanthamoeba species are an important cause of microbial keratitis that may cause severe ocular inflammation and visual loss. The first cases were recognized in 1973, but the disease remained very rare until the 1980s, when an increase in incidence mainly associated with contact lens wear was reported.
C D, Illingworth, S D, Cook
openaire   +2 more sources

ACANTHAMOEBA SCLEROKERATITIS

The Pediatric Infectious Disease Journal, 1986
Acanthamoeba infection of the cornea is an entity now recognized with increasing frequency. We saw two cases of Acanthamoeba sclerokeratitis in contact lens wearers in whom scleritis (anterior and posterior) played a central role in the clinical course of the disease.
M J, Mannis   +4 more
openaire   +2 more sources

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