Results 41 to 50 of about 32,441 (268)

Understanding Acanthamoeba Keratitis: An In-Depth Review of a Sight-Threatening Eye Infection

Microorganisms
Acanthamoeba keratitis (AK) is a rare but potentially sight-threatening corneal infection caused by the Acanthamoeba parasite. This microorganism is found ubiquitously in the environment, often in freshwater, soil, and other sources of moisture.
F. Petrillo, Antonia Tortori, V. Vallino, Marilena Galdiero, A. Fea, Ugo de Sanctis, M. Reibaldi   +6 more
semanticscholar   +1 more source

Comparative genomic analysis of Acanthamoeba from different sources and horizontal transfer events of antimicrobial resistance genes

mSphere
Acanthamoeba species are among the most common free-living amoeba and ubiquitous protozoa, mainly distributed in water and soil, and cause Acanthamoeba keratitis (AK) and severe visual impairment in patients.
Xinyi Ling, Xiaobin Gu, Yue Shen, Chunyan Fu, Yumei Zhou, Yiling Yin, Yanqiu Gao, Yiwei Zhu, Yongliang Lou, Meiqin Zheng   +9 more
doaj   +1 more source

Zooming in on the intracellular microbiome composition of bacterivorous Acanthamoeba isolates

ISME Communications
Acanthamoeba, a free-living amoeba in water and soil, is an emerging pathogen causing severe eye infection known as Acanthamoeba keratitis. In its natural environment, Acanthamoeba performs a dual function as an environmental heterotrophic predator and ...
B. Rayamajhee, Mark D. P. Willcox, Savitri Sharma, R. Mooney, Constantinos Petsoglou, P. Badenoch, S. Sherchan, Fiona L Henriquez, Nicole A Carnt   +8 more
semanticscholar   +1 more source

Evaluating Alternate Methods of Determining the Antimicrobial Efficacy of Contact Lens Care Products against Acanthamoeba Trophozoites

Pathogens, 2021
Acanthamoeba keratitis (AK) is a serious ocular infection caused by a ubiquitous free-living amoeba, Acanthamoeba. This infection often results in extensive corneal damage and blindness, and is notoriously difficult to cure.
Allison Campolo, Paul Shannon, Monica Crary   +2 more
doaj   +1 more source

Antiamoebic activity of plant-based natural products and their conjugated silver nanoparticles against Acanthamoeba castellanii (ATCC 50492)

AMB Express, 2020
Acanthamoeba spp. are the causative agent of Acanthamoeba keratitis and granulomatous amoebic encephalitis (GAE). The current options to treat Acanthamoeba infections have limited success.
Areeba Anwar, E. Ting, Ayaz Anwar, Noor ul Ain, S. Faizi, M. Shah, N. Khan, R. Siddiqui   +7 more
semanticscholar   +1 more source

Acanthamoeba induces cell-cycle arrest in host cells

, 2004
Acanthamoeba can cause fatal granulomatous amoebic encephalitis (GAE) and eye keratitis. However, the pathogenesis and pathophysiology of these emerging diseases remain unclear.
Alsam, S., Stins, M., Khan, Naveed Ahmed, Sissons, J., Kim, K.S., Jayasekera, S.   +5 more
core   +1 more source

Identification and genotyping of Acanthamoeba spp. in the water resources of western Iran

Parasite Epidemiology and Control, 2023
Background: Acanthamoeba spp. is opportunistic amoeba that resides in water, soil, and air. Some pathogenic genotypes of the genus of Acanthamoeba can cause granulomatous amoebic encephalitis (GAE) in people with a defective immune system.
Azadeh Karimi, Farnaz Kheirandish, Amirreza Javadi Mamaghani, Niloofar Taghipour, Syedeh Fatemeh Mousavi, Ali Aghajani, Nozhat Zebardast, Majid Faraji, Shirzad Fallahi, Professor in Medical Parasitology   +8 more
doaj   +1 more source

Acanthamoeba castellanii induces host cell death via a phosphatidylinositol 3-kinase-dependent mechanism

, 2005
Granulomatous amoebic encephalitis due to Acanthamoeba castellanii is a serious human infection with fatal consequences, but it is not clear how the circulating amoebae interact with the blood-brain barrier and transmigrate into the central nervous ...
S. Jayasekera, N. A. Khan, M. Stins, K. S. Kim, Alsam, S., Stins, M., Khan, Naveed Ahmed, Sissons, J., J. Sissons, Kim, K.S., Jayasekera, S., S. Alsam   +11 more
core   +1 more source

Dual-Mode Gold Nanoparticle-Based Method for Early Detection of Acanthamoeba [PDF]

, 2022
Acanthamoeba keratitis is an aggressive and rapidly progressing ocular pathology whose main risk factor is the use of contact lenses. An early and differential diagnosis is considered the main factor to prevent the progression and improve the prognosis ...
Guerreiro, Joana Rafaela L., Almudena Crooke, Marta Prado, Crooke Álvarez, Almudena, Prado, Marta, Carlos Carpena-Torres, Pastrana, Cristina, Toral, Fernando, Elumalai, Monisha, Gonzalo Carracedo, A, Crooke, Crooke, Almudena, Carracedo Rodriguez, Juan Gonzalo, Pastrana Robles, Cristina, J. Rafaela L. Guerreiro, Huete Toral, Fernando, Monisha Elumalai, Guerreiro, J. Rafaela L., Fernando Huete-Toral, Carracedo, Gonzalo, Cristina Pastrana, Carpena Torres, Carlos, Guerreiro, Joana, Carpena-Torres, Carlos, Huete-Toral, Fernando, Guerreiro, Joana Rafaela   +25 more
core   +1 more source

Detection and Identification of Acanthamoeba and Other Nonviral Causes of Infectious Keratitis in Corneal Scrapings by Real-Time PCR and Next-Generation Sequencing-Based 16S-18S Gene Analysis

Journal of Clinical Microbiology, 2020
Acanthamoeba is a free-living amoeba of extensive genetic diversity. It may cause infectious keratitis (IK), which can also be caused by bacteria, fungi, and viruses. ABSTRACT Acanthamoeba is a free-living amoeba of extensive genetic diversity.
D. B. Holmgaard, C. Barnadas, Seyed Hossein Mirbarati, L. O'Brien Andersen, H. Nielsen, C. R. Stensvold   +5 more
semanticscholar   +1 more source