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Journal of Dermatological Treatment, 2008 Acanthosis nigricans is a mucocutaneous dermatosis characterized by hyperpigmentation and a velvety papillomatous hyperkeratosis. It is frequently associated with systemic diseases including malignancy and endocrinal disorders.
Stamatis Gregoriou
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Journal of Basic and Clinical Physiology and Pharmacology, 1998
Acanthosis nigricans is a lesion affecting localized areas of the skin in persons with obesity and/or hyperinsulinemia. Roughening of the skin correlates with histological papilomatosis and the apparent darkening is due to hyperkeratosis. Biochemical mechanisms for developing this hyperplastic lesion are unclear, but likely involve local cutaneous ...
C A, Stuart +5 more
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Acanthosis nigricans is a lesion affecting localized areas of the skin in persons with obesity and/or hyperinsulinemia. Roughening of the skin correlates with histological papilomatosis and the apparent darkening is due to hyperkeratosis. Biochemical mechanisms for developing this hyperplastic lesion are unclear, but likely involve local cutaneous ...
C A, Stuart +5 more
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Acanthosis nigricans in achondroplasia
American Journal of Medical Genetics Part A, 2018Acanthosis nigricans (AN) in those with achondroplasia has been reported occasionally in the literature previously. Other disorders arising from constitutive activation of FGFR3 also manifest AN at various frequencies. We assessed the prevalence of AN in a sequential series of 477 individuals with achondroplasia.
Cory J. Smid +4 more
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Journal of the American Academy of Dermatology, 1994
Acanthosis nigricans is a mucocutaneous eruption that occurs in a strikingly exuberant form as a marker for a highly malignant and rapidly fatal internal cancer. Recently, it has been recognized that acanthosis nigricans may also be a relatively common marker for increased long-term risk of the less dramatic but potentially serious systemic disorders ...
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Acanthosis nigricans is a mucocutaneous eruption that occurs in a strikingly exuberant form as a marker for a highly malignant and rapidly fatal internal cancer. Recently, it has been recognized that acanthosis nigricans may also be a relatively common marker for increased long-term risk of the less dramatic but potentially serious systemic disorders ...
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Acanthosis Nigricans with Endocrinopathy
JAMA, 1961RECENTLY Winkelmann, Scheen, and Underdahl 1 of the Mayo Clinic reported that "among 29 patients who had blackish-brown, verrucous lesions of benign pubertal or postpuberal acanthosis nigricans, there were 9 with endocrinopathy in the form of pituitary adenoma, SteinLeventhal syndrome, Addison's disease, or diabetes mellitus." The following reports a ...
R C, MOEHLIG, N, RACHMANINOFF
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SIGNIFICANCE OF ACANTHOSIS NIGRICANS
Archives of Dermatology, 1952ACANTHOSIS nigricans is significant not only to dermatology; its ramifications and associations extend to many branches of medicine. This paper elaborates on aspects of acanthosis nigricans which are of interest to various medical disciplines. Two types of acanthosis nigricans, a dermatosis benign in itself, are observed.
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Journal of the American Academy of Dermatology, 2007
Acanthosis nigricans is a velvety thickening of the epidermis that primarily affects the axillae, posterior neck fold, flexor skin surfaces, and umbilicus, and infrequently is diffuse with involvement of the mucosal surfaces. It is increasingly seen in children and adolescents who are obese, and can serve as a cutaneous marker of insulin resistance and
Smeeta, Sinha, Robert A, Schwartz
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Acanthosis nigricans is a velvety thickening of the epidermis that primarily affects the axillae, posterior neck fold, flexor skin surfaces, and umbilicus, and infrequently is diffuse with involvement of the mucosal surfaces. It is increasingly seen in children and adolescents who are obese, and can serve as a cutaneous marker of insulin resistance and
Smeeta, Sinha, Robert A, Schwartz
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Generalized Acanthosis nigricans
Dermatologica, 2009A patient suffering from an advanced and inoperable gastric carcinoma developed an unusual paraneoplastic syndrome, consisting of intensive pruritus, acanthosis nigricans, sign of Leser-Trélat (seborrhoic keratoses and freckles), warty and papillomatous excrescences, palmoplantar hyperkeratosis and florid papillomatous and granular lesions of the mouth
V C, Andreev, L, Boyanov, N, Tsankov
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International Journal of Dermatology, 1996
A 15‐year‐old girl (Case 1), presented with thickening and hyperpigmentation of the skin over the dorsa of both hands and feet, and the periorbital area. Hyperpigmentation at the above sites was noticed 6 months after birth; gradually the skin became thickened over the years.
S, Dhar, G, Dawn, A J, Kanwar, R, Nada
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A 15‐year‐old girl (Case 1), presented with thickening and hyperpigmentation of the skin over the dorsa of both hands and feet, and the periorbital area. Hyperpigmentation at the above sites was noticed 6 months after birth; gradually the skin became thickened over the years.
S, Dhar, G, Dawn, A J, Kanwar, R, Nada
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A Newborn with Acanthosis Nigricans: Can It Be Crouzon Syndrome with Acanthosis Nigricans?
Pediatric Dermatology, 2010Crouzon syndrome is a craniosynostosis syndrome, characterized by cloverleaf skull, hypertelorism, exophthalmos, external strabismus, parrot-beaked nose, short upper lip, hypoplastic maxilla, and mandibular prognathism. The 5% of individuals with Crouzon syndrome who have pigmentary changes in the skin are said to have Crouzon syndrome with acanthosis ...
Sheetal, Sharda +4 more
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