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Generalized idiopathic acanthosis nigricans treated with acitretin
Journal of Dermatological Treatment, 2006 Generalized idiopathic acanthosis nigricans is a rare form of acanthosis nigricans. This form may be familial or nonfamilial and begins at birth or in early childhood.
Cuyan Demirkesen
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Oral Surgery, Oral Medicine, Oral Pathology, 1987
Acanthosis nigricans (AN) is a well-defined skin disorder characterized by velvety hyperkeratotic macules that can be accompanied by various degrees of pigmentation. Other manifestations of AN are marked papillomatous growths and deep skin markings. These changes can affect the entire skin but preferentially are observed in the axilla, neck, genitals ...
H O, Sedano, R J, Gorlin
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Acanthosis nigricans (AN) is a well-defined skin disorder characterized by velvety hyperkeratotic macules that can be accompanied by various degrees of pigmentation. Other manifestations of AN are marked papillomatous growths and deep skin markings. These changes can affect the entire skin but preferentially are observed in the axilla, neck, genitals ...
H O, Sedano, R J, Gorlin
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Journal of Basic and Clinical Physiology and Pharmacology, 1998
Acanthosis nigricans is a lesion affecting localized areas of the skin in persons with obesity and/or hyperinsulinemia. Roughening of the skin correlates with histological papilomatosis and the apparent darkening is due to hyperkeratosis. Biochemical mechanisms for developing this hyperplastic lesion are unclear, but likely involve local cutaneous ...
C A, Stuart +5 more
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Acanthosis nigricans is a lesion affecting localized areas of the skin in persons with obesity and/or hyperinsulinemia. Roughening of the skin correlates with histological papilomatosis and the apparent darkening is due to hyperkeratosis. Biochemical mechanisms for developing this hyperplastic lesion are unclear, but likely involve local cutaneous ...
C A, Stuart +5 more
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Journal of Investigative Dermatology, 1992 Clinical and epidemiologic evidence has shown acanthosis nigricans to be closely related to defective tissue utilization of insulin in a number of previously recognized (e.g., obesity, lipodystrophy, and leprechaunism) as well as recently characterized ...
Ponciano D Cruz, P D Cruz
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Journal of the American Academy of Dermatology, 1994
Acanthosis nigricans is a mucocutaneous eruption that occurs in a strikingly exuberant form as a marker for a highly malignant and rapidly fatal internal cancer. Recently, it has been recognized that acanthosis nigricans may also be a relatively common marker for increased long-term risk of the less dramatic but potentially serious systemic disorders ...
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Acanthosis nigricans is a mucocutaneous eruption that occurs in a strikingly exuberant form as a marker for a highly malignant and rapidly fatal internal cancer. Recently, it has been recognized that acanthosis nigricans may also be a relatively common marker for increased long-term risk of the less dramatic but potentially serious systemic disorders ...
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Acanthosis nigricans in achondroplasia
American Journal of Medical Genetics Part A, 2018Acanthosis nigricans (AN) in those with achondroplasia has been reported occasionally in the literature previously. Other disorders arising from constitutive activation of FGFR3 also manifest AN at various frequencies. We assessed the prevalence of AN in a sequential series of 477 individuals with achondroplasia.
Cory J. Smid +4 more
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Acanthosis Nigricans with Endocrinopathy
JAMA, 1961RECENTLY Winkelmann, Scheen, and Underdahl 1 of the Mayo Clinic reported that "among 29 patients who had blackish-brown, verrucous lesions of benign pubertal or postpuberal acanthosis nigricans, there were 9 with endocrinopathy in the form of pituitary adenoma, SteinLeventhal syndrome, Addison's disease, or diabetes mellitus." The following reports a ...
R C, MOEHLIG, N, RACHMANINOFF
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Systematic review of topical, laser, and oral treatments in acanthosis nigricans clinical trials
Archives of Dermatological ResearchAcanthosis nigricans (AN), with an estimated prevalence of 19.4% in the U.S., presents as hyperpigmented, velvety plaques in intertriginous regions. Acanthosis Nigricans negatively affects psychological well-being and particularly impacts skin of color ...
Kayla Zafar +2 more
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SIGNIFICANCE OF ACANTHOSIS NIGRICANS
Archives of Dermatology, 1952ACANTHOSIS nigricans is significant not only to dermatology; its ramifications and associations extend to many branches of medicine. This paper elaborates on aspects of acanthosis nigricans which are of interest to various medical disciplines. Two types of acanthosis nigricans, a dermatosis benign in itself, are observed.
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Journal of the American Academy of Dermatology, 2007
Acanthosis nigricans is a velvety thickening of the epidermis that primarily affects the axillae, posterior neck fold, flexor skin surfaces, and umbilicus, and infrequently is diffuse with involvement of the mucosal surfaces. It is increasingly seen in children and adolescents who are obese, and can serve as a cutaneous marker of insulin resistance and
Smeeta, Sinha, Robert A, Schwartz
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Acanthosis nigricans is a velvety thickening of the epidermis that primarily affects the axillae, posterior neck fold, flexor skin surfaces, and umbilicus, and infrequently is diffuse with involvement of the mucosal surfaces. It is increasingly seen in children and adolescents who are obese, and can serve as a cutaneous marker of insulin resistance and
Smeeta, Sinha, Robert A, Schwartz
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