Results 1 to 10 of about 635,089 (319)
Insulin resistance in children [PDF]
Current Opinion in Pediatrics, 2019 Purpose of review Insulin resistance (IR) is a clinical condition due to the decline in the efficiency of insulin promoting glucose uptake and utilization. The aim of this review is to provide an overview of the current knowledge on IR in children, focusing on its physiopathology, the most appropriate methods of measurement of ...
Tagi V. M., Giannini C., Chiarelli F.
openaire +5 more sources
Insulin and Insulin Resistance in Alzheimer’s Disease [PDF]
International Journal of Molecular Sciences, 2021 Insulin plays a range of roles as an anabolic hormone in peripheral tissues. It regulates glucose metabolism, stimulates glucose transport into cells and suppresses hepatic glucose production. Insulin influences cell growth, differentiation and protein synthesis, and inhibits catabolic processes such as glycolysis, lipolysis and proteolysis.
Aleksandra Sędzikowska +1 more
openaire +2 more sources
Insulin Resistance and Atherosclerosis [PDF]
Endocrine Reviews, 2006 The epidemic of obesity in the developed world over the last two decades is driving a large increase in type 2 diabetes and consequentially setting the scene for an impending wave of cardiovascular morbidity and mortality. It is only now being recognized that the major antecedent of type 2 diabetes, insulin resistance with its attendant syndrome, is ...
Nigro, Julie +3 more
openaire +5 more sources
Insulin Signaling and Insulin Resistance [PDF]
Journal of Investigative Medicine, 2013 Insulin resistance or its sequelae may be the common etiology of maladies associated with metabolic syndrome (eg, hypertension, type 2 diabetes, atherosclerosis, heart attack, stroke, and kidney failure). It is thus important to understand those factors that affect insulin sensitivity.
openaire +2 more sources
Insulin Resistance and Hypertension [PDF]
Hypertension, 2004 The association between insulin resistance and insulinemia and hypertension is controversial. We examined the relation between insulin resistance and hypertension in 564 non-Hispanic whites (NHW), 505 Hispanics (H), and 413 African Americans (AA) who participated in the Insulin Resistance Atherosclerosis Study (IRAS).
Mohammed F, Saad +9 more
openaire +2 more sources
Mechanisms of Insulin Action and Insulin Resistance [PDF]
Physiological Reviews, 2018 The 1921 discovery of insulin was a Big Bang from which a vast and expanding universe of research into insulin action and resistance has issued. In the intervening century, some discoveries have matured, coalescing into solid and fertile ground for clinical application; others remain incompletely investigated and scientifically controversial.
Max C, Petersen, Gerald I, Shulman
openaire +2 more sources
Insulin Resistance and Atherosclerosis [PDF]
Endocrinology and Metabolism Clinics of North America, 2008 Insulin resistance characterizes type 2 diabetes and the metabolic syndrome, disorders associated with an increased risk of death due to macrovascular disease. In the past few decades, research from both the basic science and clinical arenas has enabled evidence-based use of therapeutic modalities such as statins and angiotensin-converting enzyme ...
Babak, Razani +2 more
openaire +2 more sources
Endocrine, 2006 Polycystic ovary syndrome (PCOS) is the commonest endocrinopathy affecting women of reproductive age, manifested with a variety of clinical signs, none of which is pathognomonic. The association of insulin resistance and reproductive abnormalities with clinical hyperandrogenism in a woman was first demonstrated by Achard and Thiers in the "diabetes of ...
openaire +3 more sources
Updates on insulin resistance [PDF]
Expert Review of Cardiovascular Therapy, 2013 The World Congress on Insulin Resistance, Diabetes and Cardiovascular Disease is a unique multidisciplinary program held on 1-3 November 2012 in Hollywood, CA, USA. It was well attended by a large contingent of endocrinologists, cardiologists, internists, diabetologists, obstetricians/gynecologists, pediatricians, dieticians, registered nurses and ...
openaire +2 more sources
Insulin Resistance Concepts [PDF]
Diabetes Care, 2007 Perspectives on the News commentaries are now part of a new, free monthly CME activity. The Mount Sinai School of Medicine, New York, New York, is designating this activity for 2.0 AMA PRA Category 1 credits. If you wish to participate, review this article and visit www.diabetes.procampus.net to complete a posttest and receive a certificate.
openaire +2 more sources