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Effects of Hyperinsulinemia in the Primate Fetus

Diabetes, 1985
Nonhuman primate models of gestational diabetes have produced fetopathies most similar to those of the human infant of the mother with gestational diabetes (IGDM). Fetal hyperglycemia, hyperinsulinemia, macrosomia, selective organomegaly, intrauterine death, and placental hyperplasia are hallmarks of the fetopathy of the IGDM.
J B, Susa, R, Schwartz
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Insulin resistance, hyperinsulinemia and hypertension

Journal of Hypertension, 1993
Association between insulin resistance and hypertension: Insulin resistance and reactive hyperinsulinemia occur not only with obesity, impaired glucose tolerance or non-insulin-dependent (type 2) diabetes mellitus, but also in many non-obese, non-diabetic patients with essential hypertension and their currently normotensive, lean young offspring and in
Weidmann, Peter, de Courten, Maximilian, Bohlen, Lorenz   +2 more
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Obesity and hyperinsulinemia drive adipocytes to activate a cell cycle program and senesce

Nature Medicine, 2021
Qian Li, C. Hagberg, Helena Silva Cascales, Shuai Lang, M. Hyvönen, F. Salehzadeh, Ping Chen, Ida Alexandersson, Eleni Terezaki, Matthew J. Harms, Maria Kutschke, Nahida Arifen, Niels Krämer, M. Aouadi, C. Knibbe, J. Boucher, A. Thorell, Kirsty L. Spalding   +17 more
semanticscholar   +1 more source

Hyperinsulinemia and Macrosomia

New England Journal of Medicine, 1990
Macrosomia is a characteristic feature of diabetic pregnancy. The infants of mothers with diabetes mellitus (especially those with poorly controlled insulin-dependent diabetes or gestational diabet...
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Does Hyperinsulinemia Preserve Bone?

Diabetes Care, 1996
OBJECTIVE Obesity and NIDDM are each associated with increased bone mineral density (BMD). We therefore hypothesize that hyperinsulinemia is an osteogenic factor. RESEARCH DESIGN AND METHODS Subjects consisted of 411 men and 559 women aged 50–89 ...
E, Barrett-Connor, D, Kritz-Silverstein
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Hyperinsulinemia and risk of Alzheimer disease

Neurology, 2004
To explore the association between fasting insulin levels and dementia.Fasting insulin levels were measured from frozen sera using solid-phase chemiluminescent enzyme immunoassay in a sample of elderly subjects chosen at random from a cohort of persons aged 65 years and older from northern Manhattan.
Jose A, Luchsinger, Ming-Xin, Tang, Steven, Shea, Richard, Mayeux   +3 more
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Hyperinsulinemia, Insulin Resistance, and Hypertension

Journal of Cardiovascular Pharmacology, 1994
Obesity is the most common reason for insulin resistance with consequent hyperinsulinemia. Other reasons for hyperinsulinemia are type II diabetes mellitus and a genetic predisposition with a family history of hypertension. Hyperinsulinemia is considered to cause blood pressure elevation and is generally accepted as an independent risk factor for ...
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Hyperinsulinemia and Hyperfiltration in Renal Transplantation

Transplantation, 2009
Insulin-resistance hyperinsulinemia is a novel risk factor for renal disease in the general population. Glomerular hyperfiltration has been proposed as an early consequence of hyperinsulinemia.In this multicenter cohort study, we analyzed 202 patients without diabetes before or after renal transplantation during the first posttransplant year.
Porrini, E, Bayes, B, Diaz, JM, Ibernon, M, Benitez, R, Dominguez, R, Moreno, JM, Delgado, P, Lauzurica, R, Silva, I, Moreso, F, Lampreabe, I, Arias, M, Osuna, A, Torres, A   +14 more
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Hyperinsulinemia and regulation of energy balance

The American Journal of Clinical Nutrition, 1995
Recent data suggest that hyperinsulinemia with euglycemia may favor the restoration of energy balance when one gains body weight. To test the validity of this concept in humans, the data of 24 young men who had been exposed to a 353-MJ overfeeding protocol for 100 d and who were remeasured after a 4-mo follow-up were analyzed. The sample was subdivided
A, Tremblay, A, Nadeau, J P, Després, C, Bouchard   +3 more
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Insulin resistance and hyperinsulinemia in hypertension

Journal of Hypertension, 1995
GENETIC PREDISPOSITION: Insulin resistance and reactive hyperinsulinemia occur not only with obesity, impaired glucose tolerance or non-insulin-dependent (type 2) diabetes mellitus, but also in many non-obese, non-diabetic patients with essential hypertension and their currently normotensive, lean, young offspring, as well as in some other conditions ...
Weidmann, Peter, Bohlen, Lorenz, de Courten, Maximilian   +2 more
openaire   +3 more sources