Results 41 to 50 of about 49,307 (224)
Metformin Can Attenuate Beta-Cell Hypersecretion—Implications for Treatment of Children with Obesity
Metabolites, 2023 In children with obesity, insulin hypersecretion is proposed to precede insulin resistance. We investigated if metformin could be used to attenuate insulin secretion from palmitate-treated isolated islets and its implication for children with obesity ...
Quan Wen +8 more
doaj +1 more source
Food Chemistry International, EarlyView.Acha–chia–soycake biscuits improved glucose tolerance, lipid profile, insulin levels, and pancreatic integrity in HFD–STZ diabetic rats. ACSB1 and ACSB13 outperformed acarbose, showing potent antihyperglycemic, hypolipidemic, and pancreatic‐protective effects.
Oluwafunmilayo Christianah Ogunnowo +5 more
wiley +1 more source
Effects of T2DM on cancer progression: pivotal precipitating factors and underlying mechanisms
Frontiers in EndocrinologyType 2 diabetes mellitus (T2DM) is a chronic metabolic disorder affecting people worldwide. It is characterized by several key features, including hyperinsulinemia, hyperglycemia, hyperlipidemia, and dysbiosis.
Yu-Yuan Zhang +9 more
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Dietary and biomarker‐guided strategies as supportive measures in the fragile X syndrome
Food Biomacromolecules, EarlyView.Abstract The fragile X syndrome (FXS) is an inherited neurodevelopmental disorder that primarily affects males, often resulting in an IQ below 55, while about two‐thirds of females also experience intellectual disability. Physical features may include an elongated face, prominent ears, finger joint laxity, and enlarged testes in males.
Jailan E. El Halawani, Reem R. AlOlaby
wiley +1 more source
Influence of insulin resistance on renal function in patients with abdominal obesity.
Medičnì Perspektivi, 2015 The purpose of the study - to assess the role of insulin resistance in the development of initial manifestations of renal disease in patients with abdominal obesity.
T. O. Pertseva, M. K. Rokutova
doaj +1 more source
MedComm, 2021 Diet‐induced obesity, the metabolic syndrome, type 2 diabetes (DIO/MetS/T2DM), and their adverse sequelae have reached pandemic levels. In mice, DIO/MetS/T2DM initiation involves diet‐dependent increases in lipids that activate hepatic atypical PKC (aPKC)
Mini P. Sajan +5 more
doaj +1 more source
Frontiers in EndocrinologyPurposeThe short-term prognosis of hyperinsulinemia in patients with hyperlipidemia resulting in acute pancreatitis remains uncertain, so this research explores the correlation between them.Material and methodsThis study retrospectively analyzed patients
Mengjun Wang +5 more
doaj +1 more source
International Journal of Cancer, EarlyView.Over a dozen cancers have been associated with excess body mass index, primarily in mid‐to‐late adulthood. Whether obesity‐related cancer risk differs across adulthood remains unclear. Using the Sensitive Periods Model and super‐landmarking approaches, this study found that higher BMI increased obesity‐related cancer risk across ages 30–65.
Nadin K. Hawwash +13 more
wiley +1 more source
International Journal of Cancer, EarlyView.Colorectal cancer incidence and mortality have increased in the Asia‐Pacific region over the past three decades. This population‐based study in Taiwan suggests a shift of the colorectal cancer burden towards the younger generations. An age–period–cohort model revealed higher annual increases in incidence (3.58%) and mortality (1.0%) rates among ...
Yun‐Chen Tsai +3 more
wiley +1 more source
Metabolic and Endocrine Insights in Donkeys
AnimalsDonkey medicine is gaining attention due to their increased use as companion animals, in shows, asinotherapy, etc. The increasing demand and unique aspects call for specialized care, requiring new information (physiology, infectious disorders ...
Francisco J. Mendoza +2 more
doaj +1 more source