Results 1 to 10 of about 142,502 (333)
Deconstructing a Syndrome: Genomic Insights Into PCOS Causal Mechanisms and Classification
Endocrine Reviews, 2022 Polycystic ovary syndrome (PCOS) is among the most common disorders of reproductive-age women, affecting up to 15% worldwide, depending on the diagnostic criteria.
Matthew Dapas, Andrea Dunaif
exaly +2 more sources
Methylglyoxal-Dependent Glycative Stress and Deregulation of SIRT1 Functional Network in the Ovary of PCOS Mice [PDF]
Cells, 2020 Advanced glycation end-products (AGEs) are involved in the pathogenesis and consequences of polycystic ovary syndrome (PCOS), a complex metabolic disorder associated with female infertility.
Giovanna Di Emidio +10 more
doaj +3 more sources
Metabolic Syndrome and PCOS: Pathogenesis and the Role of Metabolites
Metabolites, 2021 Polycystic ovary syndrome (PCOS) is one of the most common endocrine diseases among women of reproductive age and is associated with many metabolic manifestations, such as obesity, insulin resistance (IR) and hyperandrogenism. The underlying pathogenesis
Weixuan Chen, Yanli Pang
exaly +2 more sources
The interplay between PCOS pathology and diet on gut microbiota in a mouse model
Gut Microbes, 2022 The gut microbiome has been implicated in polycystic ovary syndrome (PCOS) pathophysiology. PCOS is a disorder with reproductive, endocrine and metabolic irregularities, and several studies report that PCOS is associated with a decrease in microbial ...
Valentina Rodriguez Paris +2 more
exaly +2 more sources
Frontiers in Endocrinology, 2021 Polycystic ovary syndrome (PCOS) is a common reproductive endocrine disease. PCOS patients are characterized by hyperandrogenemia, anovulation, and metabolic dysfunction.
Jie Qiao, Yanli Pang
exaly +2 more sources
Nutrients, 2019 Polycystic ovary syndrome (PCOS) is the most common female endocrine disorder and is characterized by chronic anovulation, hyperandrogenism, and polycystic ovaries. Obesity, low-grade chronic inflammatory status, and insulin-resistance (IR) often coexist
Luigi Barrea +2 more
exaly +2 more sources
Genetic Basis of Polycystic Ovary Syndrome (PCOS): Current Perspectives
The Application of Clinical Genetics, 2019 Muhammad Jaseem Khan,1,* Anwar Ullah,1,* Sulman Basit2 1Institute of Paramedical Sciences, Khyber Medical University, Peshawar, Pakistan; 2Center for Genetics and Inherited Diseases, Taibah University Almadinah Almunawwarrah, Peshawar, Saudi Arabia*These
Khan MJ, Ullah A, Basit S
doaj +2 more sources
Current Guidelines for Diagnosing PCOS
Diagnostics, 2023 Polycystic ovary syndrome (PCOS) is the most common endocrine disorder of reproductive-aged women. Much of the confusion surrounding PCOS diagnosis stems from the broad heterogeneity of symptomology experienced by women with PCOS. The diverse features of
J. Christ, M. Cedars
semanticscholar +1 more source
Chronic Low Grade Inflammation in Pathogenesis of PCOS
International Journal of Molecular Sciences, 2021 Polycystic ovary syndrome (PCOS) is a one of the most common endocrine disorders, with a prevalence rate of 5–10% in reproductive aged women. It’s characterized by (1) chronic anovulation, (2) biochemical and/or clinical hyperandrogenism, and (3 ...
E. Rudnicka +7 more
semanticscholar +1 more source