Metabolites, 2023 Despite the beneficial effect of myo-inositol on metabolic, hormonal, and reproductive parameters of polycystic ovary syndrome (PCOS) patients, 28% to 38% could be resistant to this treatment.
Zdravko Kamenov +2 more
exaly +4 more sources
Anti-inflammatory activity and metabolite profiling of myo-inositol in LPS-stimulated macrophages. [PDF]
PLoS ONEThere has been increasing interest in using dietary bioactive substances to alleviate and reduce inflammation. This study aims to assess myo-inositol's possible anti-inflammatory effects, especially in handling conditions associated with macrophage ...
Marwa Seif +6 more
doaj +2 more sources
Myo-Inositol and Its Derivatives: Their Emerging Role in the Treatment of Human Diseases
Frontiers in Pharmacology, 2019 Myo-inositol has been established as an important growth-promoting factor of mammalian cells and animals. The role of myo-inositol as a lipotropic factor has been proven, in addition to its involvement as co-factors of enzymes and as messenger molecules ...
Dhani Raj Chhetri
exaly +3 more sources
Exogenous Myo-Inositol Promotes Sugar Beet Growth and Nutrient Uptake in Saline-Alkali Soil [PDF]
PlantsSaline-alkali stress restricts crop yield by disrupting nutrient and water uptake, ionic balance, and oxidative homeostasis. Although myo-inositol enhances tolerance to abiotic stress, its role in sugar beet (Beta vulgaris L.) under saline-alkali ...
Liyang Wang +3 more
doaj +2 more sources
Myo-Inositol: Pharmacokinetics, Biological Functions, and Therapeutic Potential in Liver Protection: Insights from Preclinical Models [PDF]
AntioxidantsMyo-inositol, the most common stereoisomer of inositol, plays an important role in many physiological processes, such as cell signaling, regulation of glucose and lipid metabolism, and protection of cells against oxidative stress. The main focus has been
Tomasz Antonowski +2 more
doaj +2 more sources
Myo-Inositol and Its Derivatives: Their Roles in the Challenges of Infertility [PDF]
BiologyMyo-inositol (MYO) and D-chiro-inositol (DCI) are the two most significant isomeric forms of inositol, playing a critical role in intracellular signaling. MYO is the most abundant form of inositol in nature; DCI is produced from MYO through epimerization
Martina Placidi +4 more
doaj +2 more sources
The role of the myo-inositol for the prevention of the gestational diabetes mellitus: systematic review [PDF]
Revista Brasileira de Ginecologia e ObstetríciaObjective: This review evaluated myo-inositol supplementation's effectiveness in pregnant women at high risk for Gestational Diabetes Mellitus (GDM). Sources: A systematic search in PubMed/MedLine, Cochrane, and VHL databases was conducted using the ...
Thamyris Thé de Holanda +6 more
doaj +2 more sources
HarmGR13 mediates myo-inositol taste perception in Helicoverpa armigera larvae. [PDF]
PLoS GeneticsMyo-inositol, a sugar alcohol produced by most plants, serves as a nutrient and feeding stimulant for many phytophagous insects. Inositol-sensitive taste sensilla have been characterized in many Lepidoptera larvae, but their molecular bases remain ...
Yu-Sheng Tan +5 more
doaj +2 more sources
The Role of Inositol in Thyroid Physiology and in Subclinical Hypothyroidism Management
Frontiers in Endocrinology, 2021 Myo-Inositol (MYO) is the most abundant stereoisomer of inositols’ family, cyclic polyols with 6 hydroxyl groups. Myo-Inositol has a relevant role in thyroid function and autoimmune diseases, as a precursor of phosphoinositides that takes part in the ...
Salvatore Benvenga +7 more
doaj +1 more source
Overexpression of MdMIPS1 enhances drought tolerance and water-use efficiency in apple
Journal of Integrative Agriculture, 2022 Myo-inositol and its derivatives play important roles in the tolerance of higher plants to abiotic stresses, and myo-inositol-1-phosphate synthase (MIPS) is the rate-limiting enzyme in myo-inositol biosynthesis. In this study, we found that increased myo-
Ling-yu HU +6 more
doaj +1 more source