D-chiro-inositol, an aromatase down-modulator, increases androgens and reduces estrogens in male volunteers: a pilot study [PDF]
Basic and Clinical Andrology, 2021 Résumé Contexte L’insuffisance en androgènes affecte les hommes à l’âge adulte, causant plusieurs effets nocifs aux niveaux reproductif et comportemental. Puisque l’aromatase est.
Giovanni Monastra +5 more
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Stereoselective Voltammetric Biosensor for Myo-Inositol and D-Chiro-Inositol Recognition [PDF]
Sensors, 2023 This paper describes the development of a simple voltammetric biosensor for the stereoselective discrimination of myo-inositol (myo-Ins) and D-chiro-inositol (D-chiro-Ins) by means of bovine serum albumin (BSA) adsorption onto a multi-walled carbon ...
Cristina Tortolini +6 more
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D-Chiro-Inositol Regulates Insulin Signaling in Human Adipocytes [PDF]
Frontiers in Endocrinology, 2021 D-Chiro-Inositol (D-Chiro-Ins) is a secondary messenger in the insulin signaling pathway. D-Chiro-Ins modulates insulin secretion, the mitochondrial respiratory chain, and glycogen storage.
Maria Magdalena Montt-Guevara +6 more
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New Insights into the Activities of D-Chiro-Inositol: A Narrative Review [PDF]
Biomedicines, 2021 D-chiro-inositol (DCI) is a natural compound detectable in cell membranes, which is highly conserved as a biological signaling molecule. In mammals, its function is primarily characterized in the intracellular transduction cascade of insulin.
Riccardo Gambioli +5 more
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Inositols in Insulin Signaling and Glucose Metabolism [PDF]
International Journal of Endocrinology, 2018 In the past decades, both the importance of inositol for human health and the complex interaction between glucose and inositol have been the subject of increasing consideration. Glucose has been shown to interfere with cellular transmembrane transport of
Arturo Bevilacqua, Mariano Bizzarri
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The Effectiveness of Myo-Inositol and D-Chiro Inositol Treatment in Type 2 Diabetes [PDF]
International Journal of Endocrinology, 2016 Inositol has been used as a supplement in treating several pathologies such as PCOS, metabolic syndrome, and gestational diabetes. Both myo-inositol and its isomer d-chiro-inositol showed insulin mimetic effects in conditions of insulin resistance.
Basilio Pintaudi +2 more
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Myoinositol and D-Chiro Inositol in Improving Insulin Resistance in Obese Male Children: Preliminary Data [PDF]
International Journal of Endocrinology, 2016 Myoinositol and D-chiro inositol, which are inositol isomers, have been shown to possess insulin-mimetic properties and to improve insulin resistance, especially in women with polycystic ovary syndrome.
Mario Mancini +5 more
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Does ovary need D-chiro-inositol? [PDF]
Journal of Ovarian Research, 2012 Backgroud Polycystic Ovary Syndrome (PCOS) is a multifactorial pathology that affects 10% of the women in reproductive age being the main cause of infertility due to menstrual dysfunction.
Isabella Rosalbino, Raffone Emanuela
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Advances in the management of osteopenia: a case series [PDF]
Journal of Medical Case ReportsBackground Osteopenia is a pre-pathological condition characterized by reduced bone mineral density that may lead to increased fracture risk and to the onset of osteoporosis. Standard treatments for managing osteopenia include supplementation of calcium,
Maurizio Nordio, Roberto Baldelli
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Cyclitols in maturing grains of wheat, triticale and barley [PDF]
Acta Societatis Botanicorum Poloniae, 2011 In the present study, the feeding of stem-flag leaf-ear explants of wheat, triticale and barley with d-chiro-inositol and d-pinitol was used for modification of the composition of soluble carbohydrates in grains without genetic transformation of plants ...
Lesław B. Lahuta, Joanna Goszczyńska
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