Stereoselective Voltammetric Biosensor for Myo-Inositol and D-Chiro-Inositol Recognition [PDF]
Sensors, 2023 This paper describes the development of a simple voltammetric biosensor for the stereoselective discrimination of myo-inositol (myo-Ins) and D-chiro-inositol (D-chiro-Ins) by means of bovine serum albumin (BSA) adsorption onto a multi-walled carbon ...
Riccarda Antiochia +2 more
exaly +4 more sources
D-chiro-inositol, an aromatase down-modulator, increases androgens and reduces estrogens in male volunteers: a pilot study [PDF]
Basic and Clinical Andrology, 2021 Résumé Contexte L’insuffisance en androgènes affecte les hommes à l’âge adulte, causant plusieurs effets nocifs aux niveaux reproductif et comportemental. Puisque l’aromatase est.
Giovanni Monastra +5 more
doaj +2 more sources
D-Chiro-Inositol Regulates Insulin Signaling in Human Adipocytes [PDF]
Frontiers in Endocrinology, 2021 D-Chiro-Inositol (D-Chiro-Ins) is a secondary messenger in the insulin signaling pathway. D-Chiro-Ins modulates insulin secretion, the mitochondrial respiratory chain, and glycogen storage.
Maria Magdalena Montt-Guevara +6 more
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New Insights into the Activities of D-Chiro-Inositol: A Narrative Review [PDF]
Biomedicines, 2021 D-chiro-inositol (DCI) is a natural compound detectable in cell membranes, which is highly conserved as a biological signaling molecule. In mammals, its function is primarily characterized in the intracellular transduction cascade of insulin.
Riccardo Gambioli +5 more
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The Effectiveness of Myo-Inositol and D-Chiro Inositol Treatment in Type 2 Diabetes [PDF]
International Journal of Endocrinology, 2016 Inositol has been used as a supplement in treating several pathologies such as PCOS, metabolic syndrome, and gestational diabetes. Both myo-inositol and its isomer d-chiro-inositol showed insulin mimetic effects in conditions of insulin resistance.
Basilio Pintaudi +2 more
doaj +2 more sources
Myoinositol and D-Chiro Inositol in Improving Insulin Resistance in Obese Male Children: Preliminary Data [PDF]
International Journal of Endocrinology, 2016 Myoinositol and D-chiro inositol, which are inositol isomers, have been shown to possess insulin-mimetic properties and to improve insulin resistance, especially in women with polycystic ovary syndrome.
Mario Mancini +5 more
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Potential Anxiolytic Effects of Selected Inositol Stereoisomers—A Narrative Review [PDF]
CellsBackground: Anxiety is a frequent clinical problem that becomes disabling when excessive or persistent. Cyclitols are naturally occurring polyhydroxy compounds, and inositols are the most abundant cyclitols in eukaryotic cells; several stereoisomers have
Maria Derkaczew +4 more
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Role of inositol and its isomers in glucose metabolism
Репродуктивная эндокринология, 2021 Despite the chemical similarities between myo-inositol and D-chiro-inositol and their synergistic effects on insulin sensitivity, they serve different functions.
O.A. Nochvinа, E.V. Slyvka
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Inositol Treatment for PCOS Should Be Science-Based and Not Arbitrary
International Journal of Endocrinology, 2020 The aim of this paper is to critically analyze the composition of many inositol-based products currently used to treat Polycystic Ovary Syndrome (PCOS).
Scott Roseff, Marta Montenegro
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A double-edge sword: the role of D-chiro-inositol in oocyte and embryo quality [PDF]
International Journal of Medical Device and Adjuvant Treatments, 2019 D-chiro-inositol is one of the nine stereoisomers of inositol, a water-soluble cyclic carbohydrate with six hydroxyl groups. Inositol has an essential function in the activation of crucial enzymes in glucose metabolism. In fact, D-chiro-inositol shortage
M. Minini, G. Monastra, S. Dinicola
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