Results 41 to 50 of about 1,452 (123)

Evaluation of the treatment with D-chiroinositol on levels of oxidative stress in pcos patients

open access: yesРепродуктивная эндокринология, 2019
Recent studies on the pathophysiology of infertility have shown that oxidative stress (OS) can be one of the causal factors. The OS is, by definition, an imbalance between the production of reactive oxygen species and antioxidant defense systems.
В. Де Лео   +2 more
doaj   +1 more source

Bioengineered Isoflavone–Probiotic Functional Foods for Sustainable Modulation of Metabolic and Reproductive Health in PCOS

open access: yesFood Bioengineering, Volume 5, Issue 1, Page 45-72, March 2026.
Synergistic isoflavone‐probiotic action modulated metabolic, microbial and ovarian pathway ABSTRACT Polycystic ovary syndrome (PCOS) is a prevalent metabolic–endocrine disorder characterized by insulin resistance, hyperandrogenism, chronic inflammation, oxidative stress, and ovarian dysfunction, with growing evidence implicating gut microbiota ...
Jeyavelkumaran Renukadevi   +4 more
wiley   +1 more source

Neuronutraceuticals for Alzheimer's Disease Treatment: A Systematic Review of Randomised Controlled Trials Over the Last 20 Years

open access: yesPhytochemicals in Food and Medicine, Volume 1, Issue 1, March 2026.
This PROSPERO‐registered review analysed 37 RCTs on neuronutraceuticals for Alzheimer's disease. Despite diverse targets—amyloid/tau, inflammation, oxidative stress, metabolism, synaptic plasticity, cholinergic and hormonal—the evidence was of low quality. RoB2 flagged attrition (86.5%) and reporting bias (81%). Current data do not support clinical use;
Mehmet Akif Topcuoglu, Esen Saka
wiley   +1 more source

Nexus of Whey Proteins, Gut Dysbiosis, and Colonic Health

open access: yesFood Science &Nutrition, Volume 14, Issue 2, February 2026.
Whey proteins possess antimicrobial and prebiotic properties that modulate gut microbiota by promoting beneficial bacteria like Bifidobacterium while suppressing pathogens. This modulation enhances short‐chain fatty acid production and strengthens intestinal barrier integrity, potentially alleviating dysbiosis‐related conditions such as colitis and ...
Tolulope Joshua Ashaolu   +4 more
wiley   +1 more source

The inositols and polycystic ovary syndrome

open access: yesIndian Journal of Endocrinology and Metabolism, 2016
This review describes the rationale, biochemical, and clinical data related to the use of inositols in polycystic ovary syndrome (PCOS). It covers studies related to the mechanism of action of myo-inositol and D-chiro-inositol (MDI), with randomized ...
Bharti Kalra, Sanjay Kalra, J B Sharma
doaj   +1 more source

Gut Microbiome Dysbiosis is Associated With Human T‐Lymphotropic Virus Type 1 (HTLV‐1) Infection and Disease Progression to HTLV‐1‐Associated Myelopathy/Tropical Spastic Paraparesis: A Cross‐Sectional Study

open access: yesSmart Medicine, Volume 5, Issue 1, February 2026.
We provide the first comprehensive analysis of changes in the gut bacteriome at different clinical stages of HTLV‐1 infection. HTLV‐1 infection is associated with a dysbiosis that includes reduced bacterial diversity and an inverted Firmicutes/Bacteroidetes ratio.
Lorena Abreu Fernandes   +8 more
wiley   +1 more source

Inositols in PCOS

open access: yesMolecules, 2020
(1) Background: Myoinositol (MI) and D-chiro-inositol (DCI) are involved in a number of biochemical pathways within oocytes having a role in oocyte maturation, fertilization, implantation, and post-implantation development.
Zdravko Kamenov, Antoaneta Gateva
doaj   +1 more source

The Concise Guide to PHARMACOLOGY 2025/26: Transporters

open access: yesBritish Journal of Pharmacology, Volume 182, Issue S1, Page S404-S496, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander   +28 more
wiley   +1 more source

Anti‐Inflammatory Role of Myo‐Inositol in Obesity: Suppression of TNF‐α‐Induced Inflammation and Monocyte Adhesion in Hypertrophic Human Adipocytes

open access: yesFood Science &Nutrition, Volume 13, Issue 9, September 2025.
Supplements targeting adipose tissue inflammation may reduce obesity‐related cardiometabolic diseases. We tested whether Myo‐Inositol (MYO), a carbocyclic sugar with insulin‐sensitizing effects, reduces adipose tissue inflammation using an in vitro model of human adipocytes stimulated with TNF‐α.
Stefano Quarta   +10 more
wiley   +1 more source

Evaluation of In Vitro Inhibitory Activity of Rye-Buckwheat Ginger Cakes with Rutin on the Formation of Advanced Glycation End-Products (AGEs)

open access: yesPolish Journal of Food and Nutrition Sciences, 2015
In this study, the relationship between the inhibitory effects of extracts from rye-buckwheat ginger cakes supplemented with low and high rutin dosage baked without or with dough fermentation step on the formation of fluorescent advanced glycation end ...
Przygodzka Małgorzata   +1 more
doaj   +1 more source

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